Results 131 to 140 of about 636,115 (299)

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

open access: yesAdvanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo   +11 more
wiley   +1 more source

Ringelmann smoke chart [PDF]

open access: yes
Supersedes: Revision of IC 7718: Kudlich, Rudolf. Ringelmann smoke chart. 1955.The Ringelmann Smoke Chart fulfills an important need in smoke abatement work and in certain problems in the combustion of fuels.

core  

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu   +4 more
wiley   +1 more source

Full-Scale Experimental Investigation of Temperature Distribution and Smoke Flow in a Road Tunnel with a Novel Water Mist Fire Fighting System

open access: yesFire
This study presents a novel water mist fire fighting system that integrates water mist sprays and water mist curtains, designed to achieve simultaneous fire suppression, thermal insulation, and smoke control.
Shouzhong Feng, Deyuan Kan, Chao Guo
doaj   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

open access: yesAdvanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin   +18 more
wiley   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

open access: yesAdvanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann   +7 more
wiley   +1 more source

Breathing Images: Representing Smoke in the Era of Record Wildfires

open access: yesArts
This article examines wildfire smoke as a critical yet disproportionately represented subject within ecocritical photography, arguing that its diffuse, persistent, and atmospheric qualities challenge dominant modes of landscape representation and ...
Andreas Rutkauskas
doaj   +1 more source

Home - About - Disclaimer - Privacy