Results 161 to 170 of about 2,195,916 (338)
Forecasting sex differences in mortality in high income nations [PDF]
To address the question of whether the sex differential in mortality will in the future rise, fall, or stay the same, this study uses the relative smoking prevalence among males and females to forecast future changes in relative smoking-attributed ...
Fred Pampel
core
Advanced Science, EarlyView.This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding +14 more
wiley +1 more source
The role of all healthcare professionals in cessation
Tobacco Induced Diseases, 2022 Jazmin Devonish +5 more
doaj +1 more source
Youth Smoking, Cigarette Prices, and Anti-Smoking Sentiment [PDF]
In this paper, we develop a new direct measure of state anti-smoking sentiment and merge it with micro data on youth smoking in 1992 and 2000. The empirical results from the cross-sectional models show two consistent patterns: after controlling for ...
Alan D. Mathios +4 more
core
The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication
Advanced Science, EarlyView.Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li +9 more
wiley +1 more source
Smoking and Lung Cancer: Report of the Tobacco Manufacturers' Standing Committee [PDF]
, 1957 I. Hieger
openalex +1 more source
Advanced Science, EarlyView.Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li +24 more
wiley +1 more source
The physical effects of smoking : preliminary experimental studies
, 1917 G. Fisher, Elmer Berry
openalex +2 more sources