Results 161 to 170 of about 1,048,233 (266)

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Is passive smoking associated with acute stress response? An observational real-world study. [PDF]

Front Public Health
Li Q, Gong R, Wang Q, Luan H, Lu W, Lu X, Li D, Sai X.   +7 more
europepmc   +1 more source

Open‐Shell Conjugated Polymers Enable Photothermoelectric Conversion and Detection of Short‐Wave Infrared Light

Advanced Science, EarlyView.
Efficient conversion and detection of short‐wave infrared (SWIR) photons are becoming increasingly important for emerging photonic and energy technologies. Here, we report an organic photothermoelectric device based on an open‐shell conjugated polymer that enables SWIR energy conversion and photon detection via the photothermoelectric effect.
Guan‐Lin Chen, Soonyong Lee, Shao‐Huan Hong, Jhih‐Min Lin, Han Young Woo, Cheng‐Liang Liu   +5 more
wiley   +1 more source

Age-dependent health risks of smoking: greater harm associated with initiation before alveolar maturation (age 24). [PDF]

J Glob Health
Liu Z, Zhao Z, Xiao Y, Xiong R, Zheng H, Liu Y, Huang Q, Zhao R, Yan J, Chen Y, Zeng H.   +10 more
europepmc   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source

A Culturally Adapted Smoking Cessation App (IndigeQuit) for American Indian and Alaska Native Adults: Protocol for a Randomized Clinical Trial. [PDF]

JMIR Res Protoc
Bricker JB, Santiago-Torres M, Sullivan BM, Mull KE, Clark HW, Kornacki C, Afraid Of Lightning-Craddock T, Seneca DS, Stanford CM, Wilcox SL, Henderson PN, Nelson L.   +11 more
europepmc   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

Secondhand smoke exposure during pregnancy: Nicotine metabolites in maternal urine and breast milk as biomarkers of infant birth weight and length, a cross-sectional study. [PDF]

Tob Induc Dis
Kunno J, Pimviriyakul P, Luangwilai T, Ong-Artborirak P, Sematong S, Chaichana T, Wiriyasirivaj B, Robson MG.   +7 more
europepmc   +1 more source