Results 201 to 210 of about 2,151,119 (340)

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

open access: yesAdvanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo   +17 more
wiley   +1 more source

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

open access: yesAdvanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu   +7 more
wiley   +1 more source

Association of Heavy Smoking With High Body Mass Index and Cardiovascular Risk Score in Japan. [PDF]

open access: yesObes Sci Pract
Takeda K   +15 more
europepmc   +1 more source

Adipose Tissue Macrophages as Initiators of Exacerbated Periodontitis in Estrogen‐Deficient Environments via the Amplifier Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
Chronic systemic inflammation, worsened by estrogen deficiency, underlies and exacerbates periodontitis. Proinflammatory macrophages within visceral adipose tissue are hyperactivated due to hyper‐DNA methylation, releasing small extracellular vesicles (sEVs) similar to those of their parent cells.
Danfeng Li   +6 more
wiley   +1 more source

Superelastic Fire‐Safe Aerogel with Hierarchical Structures via Dual Templates Aided by Microbubble Engineering

open access: yesAdvanced Science, EarlyView.
Here, a dual‐template strategy (ice and bubble template) is used to prepare fire‐safe aerogels with hierarchical structures. When the foam expansion ratio exceeds the jamming transition value in the foam system, the aerogels demonstrate superelasticity and extreme shape adaptability.
Xiaoyang Yu   +5 more
wiley   +1 more source

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