Results 211 to 220 of about 2,151,119 (340)
Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis
Advanced Science, EarlyView.Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan +13 more
wiley +1 more source
Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation
Advanced Science, EarlyView.Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng +15 more
wiley +1 more source
Smoking cessation behavior, nicotine addiction, and mental health among current smokers in Klang Valley, Malaysia- a cross-sectional questionnaire survey. [PDF]
BMC Public HealthGunasegran GSY +4 more
europepmc +1 more source
Advanced Science, EarlyView.Inspired by a high‐temperature‐resistant wire, a Super Intelligent Fireproof Yarn is developed through the technology of hierarchical textile assembly. This yarn exhibits high tensile strength, shear resistance, and excellent flame‐retardant performance, and achieves humidity‐enhanced triboelectric output, enabling it to meet the demands of extreme ...
Ying Sun +9 more
wiley +1 more source
LncRNA TMEM99 Complexes with IGF2BP2 to Inhibit Autophagy in Lung Adenocarcinoma
Advanced Science, EarlyView.LncRNA TMEM99 is significantly upregulated in lung adenocarcinoma (LUAD) and correlates with poor prognosis. It promotes LUAD cell proliferation, migration, and invasion while suppressing autophagy. Mechanistically, TMEM99 binds FUBP3 and recruits IGF2BP2 in an m⁶A‐dependent manner to stabilize and enhance p21 mRNA translation, uncovering a novel ...
Zhigang Wu +12 more
wiley +1 more source