Results 41 to 50 of about 326,600 (301)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Patterns of flavored e-cigarette use at the time of quitting smoking: comparison between American young adults (18–24 years old) and older adults (> 24 years old)

Harm Reduction Journal
Background Flavored e-cigarettes remain a controversial public health topic, with disagreement on their potential benefits and harms. In this study we compared patterns of flavor use in e-cigarettes at the time of quitting smoking between young adults ...
Konstantinos Farsalinos, Christopher Russell, Riccardo Polosa, Konstantinos Poulas, George Lagoumintzis, Anastasia Barbouni   +5 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Current smoking behavior among medical students in mainland China: a systematic review and meta-analysis

Tobacco Prevention and Cessation, 2019
This study aimed to estimate the prevalence of current smoking among medical students in mainland China through a systematic search across six electronic databases for English or Chinese studies published before May 25, 2018.
Lu Niu, Ying Liu, Dan Luo, Shuiyuan Xiao
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Multi-factorial analysis of smoking behaviour and cessation process

Lung India
Background and Objectives: Tobacco use is a major global health concern, contributing to six of the eight most common causes of death worldwide. In Turkey, the average number of cigarettes smoked per day by individuals over 15 years old surpasses the ...
Ahmet Gurbuzel, Nurgul Naurzvai, Can Ozturk   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Smoking Patterns and Their Association with Histological Subtypes in Lung Cancer Patients

Namık Kemal Tıp Dergisi
Aim: Tobacco exposure remains the most significant risk factor in the development of lung cancer. Understanding detailed smoking characteristics in affected populations provides critical insight into disease etiology and progression.
Nevin FAZLIOĞLU, Betül İNAN, Semira Sıla DEMİRER, Mehmet Kaan BELYURT, Celaleddin Arda BAĞ, Esila ARSLAN, Seyedehmahtab Mosanen TABATABAEI, Mithat FAZLIOĞLU   +7 more
doaj   +1 more source

Tobacco advertising, promotion, sponsorship and youth smoking behavior: The Indonesian 2019 Global Youth Tobacco Survey (GYTS)

Tobacco Induced Diseases, 2023
Introduction Tobacco advertisement, promotion, and sponsorship (TAPS) in all forms influences youth smoking behaviors. TAPS exposure enhances their smoking frequency and vulnerability.
Hario Megatsari, Erni Astutik, Karin Gandeswari, Susy K. Sebayang, Siti R. Nadhiroh, Santi Martini   +5 more
doaj   +1 more source

Integrating the promotion of physical activity within a smoking cessation programme: Findings from collaborative action research in UK Stop Smoking Services [PDF]

, 2010
Background: Within the framework of collaborative action research, the aim was to explore the feasibility of developing and embedding physical activity promotion as a smoking cessation aid within UK 6/7-week National Health Service (NHS) Stop Smoking ...
Everson-Hock, ES, Taylor Adrian H, Adrian H Taylor, Taylor, AH, Michael Ussher, Taylor, Adrian H, Taylor, Adrian H., Taylor, A.H., Everson-Hock, Emma S, Everson-Hock Emma S, Ussher, M, Ussher, M., Everson-Hock, E.S., Everson-Hock, Emma S., Ussher, Michael, Ussher Michael, Emma S Everson-Hock   +16 more
core   +1 more source