Results 101 to 110 of about 329,832 (294)

CellPhenoX: An Explainable Machine Learning Method for Identifying Cell Phenotypes To Predict Clinical Outcomes from Single‐Cell Multi‐Omics

Advanced Science, EarlyView.
CellPhenoX is an explainable machine learning framework that identifies cell‐specific phenotypes and interaction effects from single‐cell omics data. By leveraging interpretable models, it enables robust discovery of cell‐level phenotypes that contribute to clinical outcomes.
Jade Young, Jun Inamo, Zachary Caterer, Revanth Krishna, Fan Zhang   +4 more
wiley   +1 more source

Identity, Acculturation, and E-Cigarette Use among Bicultural Hispanic Youth and Young Adults

Health Equity
Introduction: Research suggests Hispanic/Latino/a/x/e (hereafter Hispanic) youth/young adult (YYA) tobacco use may vary by acculturation level, but few studies have explored e-cigarette use by acculturation or how bicultural identity may affect tobacco ...
Emily C. Sanders, Sarah Evans, Alex Budenz, N. Yvette Frias, Sarah Byrnes, Everly Macario   +5 more
doaj   +1 more source

Biomimetic Thermal Safety Strategies in Batteries for Electric Vehicles: from Biological Principles to Engineering Approaches

Advanced Science, EarlyView.
Biological principles derived from natural structures and functions inspire novel biomimetic strategies for battery thermal safety. This review summarizes applications of biomimetic concepts in preventing thermal runaway, highlighting design strategies that enhance thermal safety protection.
Weifeng Li, Zhongchun Wang, Yao Xue, Zhenhai Gao, Huanli Sun, Ximin Zhai, Deping Wang, Yupeng Chen   +7 more
wiley   +1 more source

The STOP Program: a Hybrid Smoking Prevention and Cessation Training for Cancer Care Providers in Colombia and Peru. [PDF]

J Cancer Educ, 2023
Tamí-Maury I, Tundealao S, Díaz V, Ochoa E, Garcia E, Rincon J, Noé-Díaz V, Castañeda C, Acosta J, Fernández M, Vidaurre T, Crowley J.   +11 more
europepmc   +1 more source

Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation

Advanced Science, EarlyView.
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng, Tianjiao Li, Hong Lin, Xiaoqin Ma, Feiye Zhou, Mingzhu Li, Yiru Wang, Shushu Wang, Jialin Tan, Junmin Chen, Yulin Yang, Jianmin Liu, Yufang Bi, Jieli Lu, Xiao Wang, Libin Zhou   +15 more
wiley   +1 more source

Hierarchically Engineered Flame‐Retardant Triboelectric Yarn Exhibiting Robust Mechanical Performance and Humidity‐Boosted Electrical Output for Firefighting Applications

Advanced Science, EarlyView.
Inspired by a high‐temperature‐resistant wire, a Super Intelligent Fireproof Yarn is developed through the technology of hierarchical textile assembly. This yarn exhibits high tensile strength, shear resistance, and excellent flame‐retardant performance, and achieves humidity‐enhanced triboelectric output, enabling it to meet the demands of extreme ...
Ying Sun, Yong Zhang, Haoyu Shi, Shujuan Wang, Jinlin Liu, Yu Luo, Cheng Zhang, Kun Zhang, Shi‐xiong Li, Wei Fan   +9 more
wiley   +1 more source

Context matters in smoking prevention: evaluating smoke-free school hours in Danish vocational schools. [PDF]

Health Promot Int, 2023
Danielsen D, Jensen TS, Kjeld SG, Bast LS, Andersen S.   +4 more
europepmc   +1 more source

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

Advanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang, Ke Fang, Wuyan Lu, Rongrong Wu, Yuanyuan Chen, Linxiao Li, Zihao Hu, Zixin Cai, Yu Jiang, Xinli Fan, Jinyi Deng, Guangpeng Liu, Zhuang Luo, Lei Cui, Shuaijun Li   +14 more
wiley   +1 more source

Exploring the mechanistic pathways of how social network influences social norms in adolescent smoking prevention interventions. [PDF]

Sci Rep, 2023
Montes F, Blanco M, Useche AF, Sanchez-Franco S, Caro C, Tong L, Li J, Zhou H, Murray JM, Sarmiento OL, Kee F, Hunter RF.   +11 more
europepmc   +1 more source

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi, Yu‐Ke Shen, Meng‐Yao Lv, Yu Sun, Yong‐Fang Lin, Zheng Wang, Xiao‐Liang Jie, Zheng Liu, Yang‐Tong Liu, Yang‐Xin Fu, Zhenhua Ren, Gui‐Zhen Wang, Guang‐Biao Zhou   +12 more
wiley   +1 more source