Results 111 to 120 of about 329,832 (294)

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning   +11 more
wiley   +1 more source

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

open access: yesAdvanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng   +4 more
wiley   +1 more source

Smoking prevention intervention with school classes in university hospital by thoracic surgeon und pulmonologist. The Zurich prevention project. [PDF]

open access: yesPrev Med Rep, 2022
Furrer K   +7 more
europepmc   +1 more source

Smoking cessation and prevention: an urgent public health priority for American Indians in the Northern Plains [PDF]

open access: green, 2002
Dorothy Gohdes   +5 more
openalex   +1 more source

GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity

open access: yesAdvanced Science, EarlyView.
This study leverages NHANES data to analyze 49 routine indicators, identifying the top 10 diagnostic markers for five major diseases and introducing GLM7, a novel indicator. Restricted cubic spline analyses, forest plot evaluations, and XGBoost modeling demonstrate conventional indicators' efficacy and GLM7's value for disease diagnosis/prediction ...
Zhihua Wang   +8 more
wiley   +1 more source

Understanding adolescent consumption patterns and attitudes towards the “puff” on the path to a smoke-free generation: a 2022 French perspective

open access: yesFrontiers in Public Health
PurposeTobacco use remains the leading preventable cause of death in France, with 75,000 deaths each year. France aims to reduce smoking and achieve a smoke-free generation by 2032.
Marin Cottin   +12 more
doaj   +1 more source

Smoking prevention programs for young people in Korean health insurance corporations [PDF]

open access: bronze, 2002
Jae-Woong Sull   +3 more
openalex   +1 more source

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