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Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert +6 more
wiley +1 more source
Abstract Clozapine is licenced for treatment‐resistant schizophrenia and psychosis in Parkinson's disease. In the United Kingdom, there is a mandatory requirement for absolute neutrophil count (ANC) and white blood cell count (WBC) monitoring to safeguard against agranulocytosis.
Stephen Murtough +29 more
wiley +1 more source
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Respiratory Medicine, 1991
Cigarette smoking is an important cause of morbidity and mortality throughout the world (1). Young people and adults take up the habit despite their awareness of its potentially harmful effects. These include chronic bronchitis, emphysema, cor pulmonale, respiratory failure, acute myocardial infarction and peripheral vascular disease.
V, Jayanthi +3 more
openaire +2 more sources
Cigarette smoking is an important cause of morbidity and mortality throughout the world (1). Young people and adults take up the habit despite their awareness of its potentially harmful effects. These include chronic bronchitis, emphysema, cor pulmonale, respiratory failure, acute myocardial infarction and peripheral vascular disease.
V, Jayanthi +3 more
openaire +2 more sources
JAMA: The Journal of the American Medical Association, 1979
To the Editor.— In a recent COMMENTARY by Richard V. Ebert, MD (240:2159, 1978), he urges physicians to try to reduce the grim toll of lung cancer, chronic bronchitis, and emphysema by encouraging their smoking patients to abstain from cigarettes. He suggests that this approach may be more productive than trying to induce young people to avoid the ...
openaire +2 more sources
To the Editor.— In a recent COMMENTARY by Richard V. Ebert, MD (240:2159, 1978), he urges physicians to try to reduce the grim toll of lung cancer, chronic bronchitis, and emphysema by encouraging their smoking patients to abstain from cigarettes. He suggests that this approach may be more productive than trying to induce young people to avoid the ...
openaire +2 more sources
Preventing cigarette smoking with youth
The Journal of Primary Prevention, 1984A repeated measures, control group design compared skills-building with attitude modification approaches to prevent cigarette smoking of 234 sixth graders. Subjects in a skills-building condition, more than those in an attitude modification condition or in a control condition, had better posttest scores on cognitive and interpersonal precursors of ...
S P, Schinke, L D, Gilchrist
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Adolescent Smoking: Onset and Prevention
Pediatrics, 1979Despite the systemic and conceptual barriers to effective preventive actions, some progress is beginning to be made in preventing adoption of self-destructive behaviors during adolescence. Application of the concept of psychological inoculation against social environmental factors that influence young people to adopt unhealthy life-styles is showing ...
A L, McAlister, C, Perry, N, Maccoby
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Pediatrics, 1968
In the Newsletter of January 1, 1968, the American Academy of Pediatrics reported that the executive board strongly endorsed time American Cancer Society's anti-smoking resolution. Personally, I cannot agree with the approach of the resolution to the public health hazard of smoking.
openaire +1 more source
In the Newsletter of January 1, 1968, the American Academy of Pediatrics reported that the executive board strongly endorsed time American Cancer Society's anti-smoking resolution. Personally, I cannot agree with the approach of the resolution to the public health hazard of smoking.
openaire +1 more source
Skills Methods to Prevent Smoking
Health Education Quarterly, 1986School health educators have devoted much attention to cigarette smoking. Recent years have seen the testing of interventions to prevent smoking. To date, controlled studies have not evaluated the added value of skills methods for preventing smoking. This article describes such an evaluation with sixth-grade students from two schools.
S P, Schinke +4 more
openaire +2 more sources

