Results 71 to 80 of about 1,351,383 (295)

Fuzzy clustering of time series gene expression data with cubic-spline

open access: yes, 2013
Data clustering techniques have been applied to ex- tract information from gene expression data for two decades. A large volume of novel clustering algorithms have been developed and achieved great success.
Ali, Akhtar, Wang, Yu, Angelova, Maia
core   +1 more source

Challenges and Opportunities in Multi‐Method Integrated Geophysical Prospection of Buried Building Remains at the Sanctuary of Olympia

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT Ancient Olympia was one of the most important sanctuaries and the venue for the Olympic Games in Greek and Roman times. Its remains are located in the Olympia Terrace (Peloponnese, Greece) at the present‐day confluence of the rivers Alpheios and Kladeos at the base of Mount Kronos.
Sarah Bäumler   +10 more
wiley   +1 more source

On the Prediction of pDNA Productivity Across Diverse Bioprocesses Using Ensemble Hybrid Models

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The global demand for plasmid DNA (pDNA) is rapidly increasing due to its key role in the manufacture of mRNA vaccines and advanced therapy medicinal products (ATMPs). However, the reliance on suboptimal batch and/or fed‐batch processes, as well as the diversity and increasing complexity of plasmid constructs pose significant challenges during
Nikolaos Stratis   +2 more
wiley   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino   +6 more
wiley   +1 more source

Estimation of a regression spline sample selection model [PDF]

open access: yes, 2013
It is often the case that an outcome of interest is observed for a restricted non-randomly selected sample of the population. In such a situation, standard statistical analysis yields biased results.
Marra, Giampiero   +5 more
core   +1 more source

Real‐Time Biomass Estimation in High‐Density Yeast Fermentations Using Soft Sensor Modeling

open access: yesBiotechnology and Bioengineering, EarlyView.
Accurate biomass measurements, both offline and online, are essential to improve prediction and control in yeast fermentation. This study develops regression‐based predictive models to correlate offline measurements (Dry Cell Weight and OD600 from a spectrophotometer) with online OD860 probe signals to provide accurate real‐time biomass estimations and
Ana G. Del Hierro   +3 more
wiley   +1 more source

Direct Determination of Smoothing Parameter for Penalized Spline Regression

open access: yesJournal of Probability and Statistics, 2014
Penalized spline estimator is one of the useful smoothing methods. To construct the estimator, having goodness of fit and smoothness, the smoothing parameter should be appropriately selected. The purpose of this paper is to select the smoothing parameter
Takuma Yoshida
doaj   +1 more source

Spline Semiparametric Regression Models

open access: yesJournal of Kufa for Mathematics and Computer, 2015
In this paper, we study semiparametric regression models with spline smoothing, and determining the numbers of knots and their locations by using some statistical criteria, a simulation model has been performed.
Ameera Jaber Mohaisen   +1 more
doaj   +1 more source

Lifespan Pancreas Morphology for Control Versus Type 2 Diabetes Using AI on Largescale Clinical Imaging

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Understanding how pancreas size and shape change with normal aging is critical for establishing a baseline to detect deviations in type 2 diabetes and other pancreatic disease. We measure pancreas size and shape using morphological measurements from early development through aging (ages 0–90).
Lucas W. Remedios   +13 more
wiley   +1 more source

Performance of robust GCV and modified GCV for spline smoothing

open access: yes, 2012
While it is a popular selection criterion for spline smoothing, generalized cross-validation (GCV) occasionally yields severely undersmoothed estimates.
Anderssen, R.S.   +2 more
core  

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