ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou +4 more
wiley +1 more source
Experimental assessment of large mammal population estimates from airborne thermal videography
Wildlife resource management requires reliable, fast, and affordable methods of surveying wildlife populations to develop and adaptively adjust policies. Thermal video from drones can yield high rates of detection over large areas with relative speed and safety.
Julia S. McElhinny +7 more
wiley +1 more source
All‑cause excess mortality in Germany peaked during the late‑2022 influenza period, exceeding peaks during SARS‑CoV‑2 waves (2020-2023). [PDF]
Heudorf U, Kowall B.
europepmc +1 more source
Identification of Yeast Protein Sequences With Similarity to the ESCRT‐III Protein Snf7
ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
Thomas Brune, Ralf Kölling
wiley +1 more source
Gut microbial composition varies with host metabolic phenotype in juvenile Atlantic salmon. [PDF]
Lindsay EC +6 more
europepmc +1 more source
Enhancing generalized spectral clustering with embedding Laplacian graph regularization
Abstract An enhanced generalised spectral clustering framework that addresses the limitations of existing methods by incorporating the Laplacian graph and group effect into a regularisation term is presented. By doing so, the framework significantly enhances discrimination power and proves highly effective in handling noisy data.
Hengmin Zhang +5 more
wiley +1 more source
Causal genes for osteoporosis: Mendelian randomization analysis with multilayer xQTL data. [PDF]
Yu F, Wan X, Qiu J.
europepmc +1 more source
Life history attributes influencing metabolic variation in an estuarine fish
Read the free Plain Language Summary for this article on the Journal blog. Abstract Considering that energy availability and oxygen transport potential are limited in supplying metabolic requirements, all animals face trade‐offs between competing metabolic demands.
Elizabeth C. Hoots +3 more
wiley +1 more source
Multi-Omics Mendelian Randomization and Colocalization Reveal Key Glycolipid Metabolism-Related Genes in Gestational Diabetes Mellitus. [PDF]
Lin X, Zheng J, Qin N, Li Y.
europepmc +1 more source
Read the free Plain Language Summary for this article on the Journal blog. Abstract The biogeography of ectotherms is greatly influenced by their thermal tolerance, which is expected to be tightly coupled to aerobic performance. However, preferred temperatures of ectotherms often deviate substantially from aerobic performance optima. This suggests that
Analisa Lazaro‐Côté +6 more
wiley +1 more source

