Results 101 to 110 of about 16,785 (258)

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Exploring knowledge, confidence and barriers to evidence-based practice implementation of self-management strategy for low back pain during chiropractic training in France: a mixed method study

BMC Complementary Medicine and Therapies
Introduction Non-specific low back pain (NSLBP), with or without radiation, is a leading cause of global disability. International guidelines recommend that healthcare providers extend self-management support (SMS) to patients to alleviate pain and ...
Sylvain Pigeon, Arnaud Lardon, André Bussières   +2 more
doaj   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

WhatsApp Versus SMS for 2-Way, Text-Based Follow-Up After Voluntary Medical Male Circumcision in South Africa: Exploration of Messaging Platform Choice

JMIR Formative Research
BackgroundTelehealth is growing, especially in areas where access to health facilities is difficult. We previously used 2-way texting (2wT) via SMS to improve the quality of postoperative care after voluntary medical male ...
Isabella Fabens, Calsile Makhele, Nelson Kibiribiri Igaba, Sizwe Hlongwane, Motshana Phohole, Evelyn Waweru, Femi Oni, Madalitso Khwepeya, Maria Sardini, Khumbulani Moyo, Hannock Tweya, Mourice Barasa Wafula, Jacqueline Pienaar, Felex Ndebele, Geoffrey Setswe, Tracy Qi Dong, Caryl Feldacker   +16 more
doaj   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Establishment of amachine learning-based precision recruitment method at the county level

Zhongguo shuxue zazhi
[Objective] To establish a machine learning-based precision blood donor recruitment model at the county level and assess its generalizability and applicability.
FU Xiaoyan, ZHANG Zihan, ZHAO Fang, ZHOU Chunlan, LIANG Wenbiao, YU Cheng, YAN Yingzhi, SI Wei, TAN Weibin, XUE Hui   +9 more
doaj   +1 more source

NIST TAC SM-KBP 2019 System Description: JHU/UR Framework [PDF]

, 2019
We designed and constructed a pipeline system for the Streaming Multimedia Knowledge Base Population (SM-KBP) 2019 evaluation. Our pipeline consists of a series of Information Extraction and Machine Translation components, supporting the population of knowledge graphs from a multilingual corpus (see Figure 1).
Chen, Yunmo, Ebner, Seth, Chen, Tongfei, Xia, Patrick, Stengel-Eskin, Elias, Su, Tzu-Ray, Hu, J, Holzenberger, Nils, Culkin, Ryan, Harman, Craig, Thomas, Max, Lippincott, Thomas, White, Aaron, Rawlins, Kyle, van Durme, Benjamin   +14 more
openaire   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen, Tony B. Huang, Catherine E. Davey, Elias Salzer, Gerjo J. V. M. Van Osch, Sandra J. Shefelbine, Marcus G. Pandy, Kathryn S. Stok   +7 more
wiley   +1 more source