Results 201 to 210 of about 16,785 (258)

Co-Design and Development of the SmilesUp Text Messaging Intervention Using Behavioral Theory to Support Parents of Children With Early Childhood Caries: Mixed Methods Study. [PDF]

JMIR Pediatr Parent
Chen R, Irving MJ, Tsai C, Christian B, Kumar H, Masoe A, Prabhu N, Sohn W, Spallek H, Chow CK.   +9 more
europepmc   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Effectiveness of the Components of a Digital Multiple Health Behavior Change Intervention Among Individuals Seeking Help Online (Coach): Factorial Randomized Trial. [PDF]

J Med Internet Res
Crawford J, Åsberg K, Blomqvist J, Lundgren O, Henriksson H, Henriksson P, Bendtsen P, Löf M, Bendtsen M.   +8 more
europepmc   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Scaling Smart: The Potential of Digital Strategies to Promote Breastfeeding in Low- and Middle-Income Countries. [PDF]

Matern Child Nutr
Bessey D.
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

ADAM: advanced design and AI-driven modeling for plant tissue culture media optimization. [PDF]

Plant Methods
Bethge H, Winkelmann T, Arteta TA, Nezami E, Pepe M, Hesami M, Jones AMP, Landin M, Gallego PP.   +8 more
europepmc   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

Advanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh, Hosni Cherif, Matthew Mannarino, Juiena Sagir, Magali Millecamps, Jean A. Ouellet, Laura S. Stone, Lisbet Haglund   +7 more
wiley   +1 more source

Behavioral Determinants and Effectiveness of Digital Behavior Change Interventions for the Prevention of Sexually Transmitted Infections and HIV: Overview of Systematic Reviews. [PDF]

J Med Internet Res
Duarte-Anselmi G, Sanduvete-Chaves S, Chacón-Moscoso S, López-Arenas D.   +3 more
europepmc   +1 more source

Biopsychosocial predictors of chronic pain after caesarean delivery: a prospective cohort evaluation of the SPACE (Sleep, Pain, Affect, Cognition, Energy)-Postpartum framework. [PDF]

BJA Open
Ciechanowicz S, Michel G, Panigrahy N, Sukhdeo H, Carvalho B, Sultan P.   +5 more
europepmc   +1 more source