Results 211 to 220 of about 299,181 (381)

Intratumoral Nerve Phased Development: A Promising Therapeutic Target

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che   +3 more
wiley   +1 more source

The Sense of Smell in Snails [PDF]

open access: green, 1906
Alfred Gradenwitz
openalex   +1 more source

Rad51 at the Crossroads: Bridging DNA Repair, Tumorigenesis, and Immune Regulation

open access: yesMed Research, EarlyView.
Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy); (2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 inhibitors, CRISPR/Cas9); and (4) combination approaches (immunotherapy). The figure is created with BioRender.com.
Zhendong Qin   +4 more
wiley   +1 more source

A Cost Function Approximation Based Large Neighborhood Search for Dynamic Medical Courier Services

open access: yesNetworks, EarlyView.
ABSTRACT Medical on‐demand couriers play an important role in urban medical services. They transport medical supplies, tests, blood, or organs between different locations in the city within a short amount of time. Transportation orders are issued spontaneously and differ in their priority and time restrictions. Since all orders must be served, the goal
Jarmo Haferkamp, Marlin W. Ulmer
wiley   +1 more source

The importance of wild meat and freshwater fish for children's nutritional intake in the Congo Basin

open access: yesPeople and Nature, EarlyView.
Abstract Wild meat and freshwater fish are widely consumed in the Congo Basin, but in some areas, they are at risk of disappearing due to unsustainable hunting and fishing and changes in their habitat. Wild meat is also at risk of being eliminated from local diets due to potential policy changes such as wild meat bans.
Amy Ickowitz   +6 more
wiley   +1 more source

A social license to operate theory for lethal control of crown‐of‐thorns starfish on the Great Barrier Reef

open access: yesPeople and Nature, EarlyView.
Abstract Outbreaks of crown‐of‐thorns starfish (COTS) have been recorded on the Great Barrier Reef (GBR) since 1962 and have considerable ecological and economic impact. Monitoring and control of COTS to predict, prevent and mitigate outbreaks is an important part of the ongoing protection of the GBR.
Henry A. Bartelet   +4 more
wiley   +1 more source

Stocking African catfish in Lake Victoria provides effective biocontrol of snail vectors of Schistosoma mansoni. [PDF]

open access: yesPLoS Negl Trop Dis
Proud R   +16 more
europepmc   +1 more source

Dysregulated mitochondrial energy metabolism drives the progression of mucosal field effects to invasive bladder cancer

open access: yesThe Journal of Pathology, EarlyView.
Abstract Multiplatform mutational and gene expression profiling complemented with proteomic and metabolomic spatial mapping were used on the whole‐organ scale to identify the molecular profile of bladder cancer evolution from field effects. Analysis of the mutational landscape identified three types of mutations, referred to as α, β, and γ.
Sangkyou Lee   +20 more
wiley   +1 more source

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