Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang+16 more
wiley +1 more source
Schistosoma japonicum in Ethiopia: Is there a need for tuning schistosomiasis surveillance in Africa? [PDF]
Abatneh Y+10 more
europepmc +1 more source
Assessing the past and future impact of a long‐term island restoration program
The IUCN Green Status of Species uses a qualitative and inferential approach to evaluate the past and expected future impacts of conservation on species recovery. Using this approach, we demonstrate the impact of a long‐term, multi‐organization conservation program in Mauritius in preventing the extinction of nine species, and the importance of ...
Rebecca E. Young+10 more
wiley +1 more source
THE RESISTANCE OF THE ONCOMELANIA SNAIL TO MOLLUSCICIDES I. SODIUM PENTACHLOROPHENATE
Y. Komiya+3 more
openalex +2 more sources
Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock+3 more
wiley +1 more source
RioM‐1: A New Calcite Reference Material for U‐Pb LA‐ICP‐MS Geochronology
Key Points RioM‐1 calcite was characterised for trace elements, U‐Pb geochronology, Sr and O isotopes using ID‐TIMS, LA‐ICP‐MS and SIMS. U‐Pb dates from ID‐TIMS and LA‐ICP‐MS across several independent laboratories returned identical results within uncertainty.
Marco Silva+10 more
wiley +1 more source
Dynamics in gut microbiota diversity, composition, and assembly reveal the adaptability of invasive snail <i>Pomacea canaliculata</i> during hibernation in rice fields. [PDF]
Yao F+5 more
europepmc +1 more source
Species traits modulate ecological release in island red devil spiders (Araneae: Dysderidae)
We studied the species ability to undergo an ecological release process in the red devil spiders (Araneae: Dysderidae) when colonising species‐depauperate environments, focusing on different aspects of their niche. We have found that the ability to expand their niche is highly dependent on the species trophic strategy, with specialist species being ...
Adrià Bellvert+5 more
wiley +1 more source
Decidual stromal cells-derived exosomes incured insufficient migration and invasion of trophoblast because of abnormal ubiquitination and degradation of Snail mediated by miR-92b-3p/USP28. [PDF]
Xiong M, He Z, Wen L, Zhao A.
europepmc +1 more source