Results 261 to 270 of about 593,238 (360)

The power of genome-wide association studies of complex disease genes: statistical limitations of indirect approaches using SNP markers [PDF]

, 2001
Jun Ohashi, K. Tokunaga
openalex   +1 more source

ESR1 Variants and Subcontinental Genomic Ancestry: Insights from the 1000 Genomes Project and Native American Populations

Clinical Pharmacology &Therapeutics, EarlyView.
The ESR1 gene is relevant in breast cancer treatments in the pharmacogenetics context. However, Native, African, and mixed populations are known to be underrepresented in genomic studies. This is particularly important given that the difference in variants' frequencies among different populations can lead to population‐specific clinical implications ...
Mariana M. Scudeler, Caíque Manóchio, Bruno Miwa, Guilherme Belfort‐Almeida, Lucas Faria‐Costa, Cesar Sanchez, Carlos Padilla, Omar Caceres, Eduardo Tarazona‐Santos, Heinner Guio, Timothy D. O'Connor, Fernanda Rodrigues‐Soares   +11 more
wiley   +1 more source

Comparison between logistic regression and machine learning algorithms on prediction of noise-induced hearing loss and investigation of SNP loci. [PDF]

Sci Rep
Lu J, Lu X, Wang Y, Zhang H, Han L, Zhu B, Wang B.   +6 more
europepmc   +1 more source

Y-chromosome SNP haplotypes suggest evidence of gene flow among caste, tribe, and the migrant Siddi populations of Andhra Pradesh, South India [PDF]

, 2001
G.V. Ramana, Bing Su, Jin Li, Lalji Singh, Ning Wang, Peter A. Underhill, Ranajit Chakraborty   +6 more
openalex   +1 more source

Implementing Pre‐Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects

Clinical Pharmacology &Therapeutics, EarlyView.
In pediatric oncology, pharmacogenetic guidelines are underutilized and the potential impact of pre‐emptive pharmacogenetic screening remains largely unexplored despite this field's need for individualized approaches. While comprehensive pharmacogenetic guidelines are not yet available for all anticancer drugs, evidence‐based recommendations exist for ...
Emma C. Bernsen, Eugène T.P. Verwiel, Maaike van der Lee, Jesse J. Swen, Marcel Santoso, Leiah J. Brigitha, Rick Admiraal, Bastiaan B.J. Tops, Alwin D.R. Huitema, Patrick Kemmeren, Jayne Y. Hehir‐Kwa, Lidwien M. Hanff, Meta H.M. Diekstra   +12 more
wiley   +1 more source

VariantFoldRNA: a flexible, containerized, and scalable pipeline for genome-wide riboSNitch prediction. [PDF]

NAR Genom Bioinform
Kirven KJ, Bevilacqua PC, Assmann SM.
europepmc   +1 more source

genotools SNP MANAGER: A New Software for Automated High-Throughput MALDI-TOF Mass Spectrometry SNP Genotyping [PDF]

, 2001
W. Pusch, K.-O. Kraeuter, Thomas Froehlich, Yves Stalgies, Markus Kostrzewa   +4 more
openalex   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Implementation of NGS and SNP microarrays in routine forensic practice: opportunities and barriers. [PDF]

BMC Genomics
Pedroza Matute S, Iyavoo S.
europepmc   +1 more source

Catalog of 46 single-nucleotide polymorphisms (SNPs) in the microsomal glutathione S-transferase 1 (MGST1) gene [PDF]

, 2001
Aritoshi Iida, S. Saito, Akihiro Sekine, S. Harigae, Satoshi Osawa, C. Mishima, Kazuhiro Kondo, Y. Kitamura, Yoshimasa Nakamura   +8 more
openalex   +1 more source