Results 231 to 240 of about 527,601 (289)

Exploring the Relationship Between MDM4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case–Control Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Our findings indicated that the rs4245739 A>C polymorphism was not associated with BC risk in the Bangladeshi population, whereas the rs1380576 C>G polymorphism was significantly associated with BC risk. This study provides new insights into the genetic factors influencing breast cancer susceptibility in the Bangladeshi population, highlighting the ...
J. M. Aousiful Islam   +7 more
wiley   +1 more source

Recent Advances in Thalassemia Research: A Comprehensive Assessment From Diagnostic Technologies to Clinical Treatment

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thalassemia, a common hereditary blood disorder causing impaired globin synthesis and related complications, has seen remarkable progress in recent years due to advancements in genomics and molecular biology. Researchers have identified various gene variants related to thalassemia and improved clinical diagnostic methods, including new genetic testing ...
Chaoqiong Zhou   +7 more
wiley   +1 more source

The population structure in the Baltic herring reflects natural selection and local adaptation. [PDF]

open access: yesProc Natl Acad Sci U S A
Goodall J   +8 more
europepmc   +1 more source

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou   +8 more
wiley   +1 more source

Pathway-Based Genetic Risk Scores Are Associated with Blood Lipids Among Young Mexican Adults. [PDF]

open access: yesNutrients
Hannon Esteves BA   +5 more
europepmc   +1 more source

Causal Interplay Between Inflammatory Cytokines and Lipid Metabolites in Serous Ovarian Carcinoma: Insights From a Genetic Association Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study utilizes a two‐sample Mendelian randomization framework to establish a causal link between circulating inflammatory proteins, blood metabolites, and the risk of serous ovarian carcinoma. Our findings identify Interleukin‐8 as a significant risk factor and demonstrate that 1‐Palmitoyl‐GPG (16:0) acts as a metabolic mediator within this ...
Chong‐ze Yang   +6 more
wiley   +1 more source

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

open access: yesJCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki   +8 more
wiley   +1 more source

Forensic Validation of the 95K SNP Panel and the Parabon Fx Forensic Analysis Platform for Identification of US Military Unknowns Using Extended Kinship Inference. [PDF]

open access: yesGenes (Basel)
Thomas JT   +7 more
europepmc   +1 more source

Investigating the impact of early adversity on perceived support from parents and friends in preadolescence: Do genetic predispositions and timing of exposure matter?

open access: yesJCPP Advances, EarlyView.
This study found that youth with a higher genetic risk for internalizing and externalizing problems were more likely to face adversity within their home, highlighting the need for risk mitigation. These associations varied by adversity type and timing. Additionally, low family income, parental divorce, and externalizing behaviours were linked to lower ...
Christina Y. Cantave   +3 more
wiley   +1 more source

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