Results 201 to 210 of about 374,167 (276)

Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller, Robin Schiemer, Lars Robbel, Michael Schmitt, Jürgen Hubbuch   +4 more
wiley   +1 more source

Mapping cellular vulnerability in Parkinson's disease using retro-AAVs and preformed α-synuclein fibrils. [PDF]

Transl Neurodegener
Geibl FF, Musa AAS, Dietrich L, Wolter H, Wokosin DL, Khudayberdiev S, Rust MB, Chen R, Dawson VL, Dawson TM, Oertel WH, Surmeier DJ, Henrich MT.   +12 more
europepmc   +1 more source

Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale, Monica Chu, Sally Wang, Divya Muthusamy, Eric Wold, Yi Liu, G. F. Payne, Tanya Tschirhart, W. E. Bentley   +8 more
wiley   +1 more source

Hybrid knowledge- and data-driven modelling for robust spike detection and sorting in human C-fiber microneurography. [PDF]

Sci Rep
Troglio A, Fiebig A, Maxion A, Kutafina E, Namer B.   +4 more
europepmc   +1 more source

A targeted antiferromagnetic nanoprobe for ultra‐sensitive magnetic resonance imaging detection of sub‐millimeter esophageal tumors

BMEMat, EarlyView.
We developed a cyclo‐RGD peptide‐conjugated antiferromagnetic nanoparticle (RANP) as a targeted T1 contrast agent. Under 9 T MRI conditions, RANP exhibited an r1 value of 1.88 mM−1 s−1 and a low r2/r1 ratio of 1.84, enabling the detection of esophageal tumors as small as 0.8 mm in vivo. Abstract Early, non‐invasive detection of esophageal cancer at sub‐
Wenkui Mo, Zeyu Liang, Bo Zhang, Lin Xiao, Xun Liu, Zhigao Yi, Shangzhi Xie, Qiyue Wang, Liang Shi, Taobo Luo, Feng Li, Leilei Wu, Yuanzhe Piao, Fangyuan Li, Jian Zeng, Daishun Ling   +15 more
wiley   +1 more source

The Effect of Modulation Enhancement Scheme on Speech Recognition in Spatial Noise Among Young Adults with Normal Hearing. [PDF]

Audiol Res
Kanagokar V, Yashu MA, Bhat JS, Pitchaimuthu AN.   +3 more
europepmc   +1 more source

Spatially resolved 23Na magnetic resonance dispersion measurement in porous media

The Canadian Journal of Chemical Engineering, EarlyView.
Quantitative 23Na MRI was employed to analyze dispersion in realistic core plug samples and was compared with the conventional breakthrough curve. 23Na MRI provided a more effective aassessment of core plug heterogeneity than the conventional method. Abstract Tracer tests are widely used in the petroleum industry to assess reservoir core plugs, relying
Rheya Rajeev, Mohammad Sadegh Zamiri, Andrés Ramírez Aguilera, Florea Marica, Laura Romero de Zerón, Bruce J. Balcom   +5 more
wiley   +1 more source