Results 261 to 270 of about 59,567 (351)

SnRNA-seq Interprets Mechanisms by which Three Glial Cell Types Influence Myelin Regeneration in Adult Drug-Resistant Epilepsy-Related Cognitive Impairment [PDF]

Lu Wang, Jiaqi Ma, Yongqian Bian, Xiao-Peng Qu, Yue Zhang, Chao Wang, Guodong Gao, Longlong Zheng, Qi-Xing Fang, Li-Jia Song, Liangliang Shen, Bei Liu   +11 more
openalex   +1 more source

Single‐cell sequencing for cancer precision medicine: From mechanism discovery to diagnosis and therapeutics

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Single‐cell sequencing overcomes bulk sequencing limitations, enabling high‐resolution multi‐omics analysis at the single‐cell level. It reveals tumour heterogeneity, identifying key subpopulations and tumour microenvironment interactions driving progression and resistance.
Yue Zhao, Hancong Li, Huanzuo Yang, Gongshuang Zhang, Xinyue Fu, Peiheng Li, Puxing He, Shuang Wu, Han Luo   +8 more
wiley   +1 more source

Comparative Transcriptomic Profiling of Corneal Compartments Using Single-Cell and Single-Nucleus Sequencing. [PDF]

Invest Ophthalmol Vis Sci
Zhao H, Li X, Zhang X, Zhou Q, Dou S, Xie L.   +5 more
europepmc   +1 more source

Astrocytic TCF7L2 Impacts Brain Osmoregulation and Restricts Neuronal Excitability

Glia, Volume 74, Issue 2, February 2026.
Astrocytic TCF7L2 impacts extracellular glutamate and glutamine levels. Loss of astrocytic TCF7L2 disrupts extracellular potassium clearance. TCF7L2‐dependent astrocytic changes reduce neuronal excitability. ABSTRACT Astrocytes differentiate and mature during postnatal development, but the molecular mechanisms linking their maturation to neuronal ...
Mariusz Popek, Krzysztof Goryca, Dorota Adamska, Joanna Urban‐Ciećko, Katarzyna Hryniewiecka, Marcin Lipiec, Tomasz Grzegorz Krawczyk, Kamil Rafalko, Alicja Ławicka, Shane A. Liddelow, Lukasz Mateusz Szewczyk   +10 more
wiley   +1 more source

Single-cell profiling defines the cellular landscape of the urinary bladder: a scoping review. [PDF]

Eur J Med Res
Padi E, Clausen AG, Kjeldgaard AB, Amoushahi M, Chamorro CI, Fossum M.   +5 more
europepmc   +1 more source

LRP4+ Astrocytes: A Unique Subpopulation Crucial for Blood Vessel Maintenance and Function in the Somatosensory Cortex of Normal and 5xFAD Mice

Glia, Volume 74, Issue 2, February 2026.
Lrp4+ astrocytes, uniquely vessel‐associated and GFAP−, are enriched in the pia. They support laminin‐α5+ basement membrane assembly and regulate vessel diameter and blood flow. They are reduced in 5xFAD brains, and their ablation worsens both vascular and Aβ pathology.
Emily Arzola, Gefei Yu, Lei Xiong, Daehoon Lee, Anika Wu, Shriya Paruchuri, Jasmine Skinner, Minghui Wang, Bin Zhang, Lin Mei, Wen‐Cheng Xiong   +10 more
wiley   +1 more source

Spatiotemporal dynamics of neuronal subtypes and their interactions with glia following intracortical electrode implantation. [PDF]

Biol Direct
Zhao Z, Duan X, Luo J, He Z, Zhang Y, Wang M, Qin J, Lin S, Chen H.   +8 more
europepmc   +1 more source

Correlated Motions in the U1 snRNA Stem/Loop 2:U1A RBD1 Complex [PDF]

, 2005
Scott A. Showalter, Kathleen B. Hall
openalex   +1 more source

Spliceosomal Factor SmF Modulates Temperature‐Mediated Flower and Leaf Size Plasticity in Arabidopsis thaliana

Plant, Cell &Environment, EarlyView.
Gregory M. Andreou‐Huotari, Mikael Brosché, Jan Hoffmann, Zoran Nikoloski, Roosa A. E. Laitinen   +4 more
wiley   +1 more source

Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała, Marta Białobrzeska, Józef Dulak, Urszula Florczyk‐Soluch   +3 more
wiley   +1 more source