Results 281 to 290 of about 59,567 (351)

Versatile and Selective Biomolecule Pulldown with Combinatorial DNA‐Crosslinked Polymers

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
We present a programmable smart polymer system for universal, sequence‐selective bioseparation under native conditions. Polymer phase separation is achieved through combinatorial DNA crosslinking, enabling the capture of DNA, RNA, or proteins in a homogeneous solution with high pulldown efficiency and near‐zero background binding.
Sarah K. Speed   +3 more
wiley   +1 more source

Hepatic adaptation to chronic metabolic stress primes tumorigenesis. [PDF]

open access: yesCell
Tzouanas CN   +33 more
europepmc   +1 more source

RNA‐Lebendzellmikroskopie via click‐funktionalisierter TriPPPro Nucleotid‐Reporter

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Die intrazelluläre Zufuhr von trans‐Cycloocten und Bicyclo[6.1.0]nonin als sterisch anspruchsvolle Gruppen für die Diels–Alder‐Reaktion mit inversem Elektronenbedarf wurde durch die Triphosphat‐Prodrug‐Strategie (TriPPPro) erreicht. Nach der Hydrolyse innerhalb der Zelle werden die modifizierten Uridine und Cytidine metabolisch in die neu entstehende ...
J. Iven H. Knaack   +6 more
wiley   +1 more source

Live‐Cell RNA Imaging via Clickable TriPPPro Nucleotide Reporters

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 2, 9 January 2026.
The intracellular delivery of trans‐cyclooctene and bicyclo[6.1.0]nonyne as sterically demanding groups for the inverse electron‐demand Diels–Alder was achieved by the triphosphate prodrug (TriPPPro) strategy. Once hydrolyzed inside cells, the modified uridines and cytidines are metabolically incorporated into nascent RNA, are labelled by a dual ...
J. Iven H. Knaack   +6 more
wiley   +1 more source

DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes

open access: yesNature Communications, 2014
Junichi Yamamoto   +6 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy