Results 111 to 120 of about 85,041 (264)

Phosphate ions modulate enzyme activity and epistatic effects in two clavulanic acid‐resistant β‐lactamase mutants

open access: yesProtein Science, Volume 34, Issue 11, November 2025.
Abstract Epistasis, the non‐additive effect of mutations, substantially undermines our ability to predict the evolutionary trajectories of enzymes. Epistatic effects are evident in the evolution of serine β‐lactamases, where synergistic mutations can enhance antimicrobial resistance.
Marko Radojković   +6 more
wiley   +1 more source

Well-posedness of Cauchy problem of fractional drift diffusion system in non-critical spaces with power-law nonlinearity

open access: yesAdvances in Nonlinear Analysis
In this article, we consider the global and local well-posedness of the mild solutions to the Cauchy problem of fractional drift diffusion system with higher-order nonlinearity. The main difficulty comes from the higher-order nonlinearity. Instead of the
Gu Caihong, Tang Yanbin
doaj   +1 more source

Coerciveness and isomorphism of discontinuous Sturm-Liouville problems with transmission conditions

open access: yesJournal of New Results in Science
This study investigates a discontinuous Sturm-Liouville boundary value problem(BVP) on two intervals with functionals and transmission conditions in the direct sum ofSobolev spaces. Moreover, it presents the differential operator generated by the problem
Murat Küçük, Mustafa Kandemir
doaj   +1 more source

Modeling the Conductivity and Diffusion Permeability of a Track-Etched Membrane Taking into Account a Loose Layer. [PDF]

open access: yesMembranes (Basel), 2022
Nichka VS   +5 more
europepmc   +1 more source

Space‐Time Boundary Elements on Graded Meshes for 3D Elastodynamics

open access: yesInternational Journal for Numerical Methods in Engineering, Volume 126, Issue 20, 30 October 2025.
ABSTRACT The solution to the elastodynamic equations in the exterior of a polygonal or polyhedral domain or a screen exhibits singularities at corners and edges. This paper presents a space‐time boundary element method in 3D on algebraically graded meshes to resolve these singularities, based on recently obtained error estimates for the weakly singular
Alessandra Aimi   +3 more
wiley   +1 more source

Secondary Plumes Formation Controlled by Interaction of Thermochemical Mantle Plumes With the Mantle Transition Zone

open access: yesGeophysical Research Letters, Volume 52, Issue 19, 16 October 2025.
Abstract The causes and global distribution of intraplate volcanism remain poorly understood, particularly the occurrence of scattered magmatism unrelated to large igneous provinces (LIPs). In this study, high‐resolution numerical simulations are employed to examine the interaction between deep thermochemical mantle plumes and the mantle transition ...
X. Zhu, A. Balázs, T. Gerya, Z. Sun
wiley   +1 more source

Error Analysis of a Pressure‐Correction Method With Explicit Time‐Stepping

open access: yesInternational Journal for Numerical Methods in Fluids, Volume 97, Issue 10, Page 1363-1378, October 2025.
We study explicit variants of this well‐established pressure‐correction scheme for solving the Navier–Stokes equations. Step 3 is replaced by an explicit time‐integration method. We give the complete error analysis for this scheme that allows for highly efficient implementations.
Utku Kaya, Thomas Richter
wiley   +1 more source

Embedding Theorems for Sobolev-Besicovitch spaces Wk,1 ap (IRs ) [PDF]

open access: yesRendiconti di Matematica e delle Sue Applicazioni, 1996
We show embedding theorems of Sobolev type for Sobolev-Besicovitch spaces Wk,q ap of almost periodic functions with q ∈ [1, 2]. The fundamental tool for the proof of the main theorem is the Hausdorff-Young theorem for a.p. functions.
G. DELL'ACQUA, P. SANTUCCI
doaj  

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