Results 101 to 110 of about 93,259 (298)

News: Intellettuali di confine

open access: yes, 2018
Paolo Scrivano, Scientific Coordinator (with Hélène Jannière) of Mapping Architectural Criticism, participated in the conference Intellettuali di confine.
Mapping Architectural Criticism
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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

News: Critique et architecture. Un état des lieux contemporain

open access: yes, 2019
Critique et architecture. Un état des lieux contemporain is the latest book by Hélène Jannière, Director and Scientific Coordinator of Mapping Architectural Criticism, published in October 2019 by the Éditions de la Villette, in Paris. Full presentation
Mapping Architectural Criticism
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Max Weber as an excuse: Curiosities of “social philosophy” [PDF]

open access: yesСоциологический журнал, 2012
The article analyzes the monograph of A.B. Rakhmanov “Social Philosophy of Max Weber”, in which criticism of Weber's sociology is used as an excuse for the revivification of Marxist social utopia.
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

News: How to Narrate the History of Architecture?

open access: yes, 2018
Paolo Scrivano, Scientific Coordinator (with Hélène Jannière) of Mapping Architectural Criticism, delivered a keynote speech at the conference How to narrate the history of architecture? Centenary of Birth of Architectural Historian Bruno Zevi (1918-2000)
Mapping Architectural Criticism
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The nature of process-produced data: towards a social-scientific source criticism

open access: yes, 1980
Probleme des Alltagslebens werden zunehmend Gegenstand administrativer Datensammlung und Verarbeitung. Diese quantitativen Daten können von der Sozialwissenschaft nur dann sinnvoll in die Arbeit einbezogen werden, wenn ihre Entstehungsbedingungen und ihr Verwendungszusammenhang in der Verwaltung berücksichtigt werden.
Bick, Wolfgang, Müller, Paul J.
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The social-scientific critical exegesis of New Testament texts : a critical assessment of the first results [PDF]

open access: yes, 2007
The article is the second of a series that aim to introduce socialscientific exegesis of New Testament texts. Social-scientific criticism represents an exegetical approach by means of which the rhetoric of texts is interpreted in light of their ...
Van Aarde, A.G. (Andries G.)
core  

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