Results 151 to 160 of about 93,259 (298)

Optimizing just-in-time adaptive interventions for interpersonal distress: mechanisms, prediction, and the challenge of engagement. [PDF]

Sci Rep
Jaremba A, O'Reilly S, Mason L, Nolte T, Shaikh M, O'Driscoll C.   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Facilitating Constructive Criticism of Established Scientific Paradigms

Scientific innovations often struggle to pass through peer review and regularly fail under certain circumstances: In its theoretical aspects, science is believed to progress through criticism and falsification, but where a dominant theoretical framework ...
Traunmüller, Hartmut,
core   +1 more source

Spread of "triad diagnostics" in suspected Shaken Baby Syndrome. [PDF]

Forensic Sci Int Synerg
Eriksson A, Stachowicz-Stencel T, Wester K.   +2 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Social criticism of Millennials in the democracy and Islamic Law perspectives

Bima, who criticized the road conditions in Lampung through his Tiktok account, shocked the Indonesian virtual world. His reckless and resentful actions were taken because he thought that the Lampung authorities did not care about the existing conditions.
Hawari, Nadirsah, Artalim, Muntaha, Ikhwani, Ahmad   +2 more
core   +1 more source

On the evolution of the company we keep: Implications for infectious disease modeling. [PDF]

PLoS Med
Mossong J.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Introducing COSIG: The Collection of Open Science Integrity Guides. [PDF]

PLoS Biol
Ozturk Y, Pirelli S, Richardson RAK.
europepmc   +1 more source

Studi Social Scientific-Criticism (Kritik Sosiologi) Terhadap 1 Korintus 3 : 10-23Yang di Relevansikan Kepada Gereja-Gereja Di Indonesia Masa Kini

Jurnal Teologi Trinity
Denominasi gereja-gereja di Indonesia sebagian besar disebabkan adanya perselisihan dan perpecahan dalam gereja karena faktor budaya, pandangan doktrin yang berbeda, politik kekuasaan dalam gereja, persoalan liturgika, sehingga terjadi konflik dan membuka denominasi gereja baru.
openaire   +1 more source