Results 131 to 140 of about 16,123,395 (250)

El movimiento estudiantil en Chile. Entrevista con Manuel Antonio Garretón

open access: yesAnuari del Conflicte Social, 2013
Observatori Conflicte Social
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Problematic Social Media Use and Self-Perception of Dental Aesthetics in Adolescents: Associations with Body Esteem, Social Anxiety and Gender. [PDF]

open access: yesPediatric Health Med Ther
Pérez Suárez MV   +6 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Entrevista a Sami Naïr. Las revoluciones árabes: islam y transición democrática (2da parte)

open access: yesAnuari del Conflicte Social, 2013
Observatori Conflicte Social
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Sex differences in social cognition: Insights from a sample enriched for social dysfunction. [PDF]

open access: yesPLoS One
Kemp KC   +10 more
europepmc   +1 more source

Entrevista a Sami Naïr. Las revoluciones árabes: islam y transición democrática (1ra parte)

open access: yesAnuari del Conflicte Social, 2013
Observatori Conflicte Social
doaj  

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