Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The effect of solution-focused approach on social adjustment and solution-focused thinking skills in nursing students who experienced violence in childhood: a single group pre-test-post test study. [PDF]
Hançer Tok H +2 more
europepmc +1 more source
Effect of peer tutoring on social adjustment among English learners with hearing impairments in special primary schools. [PDF]
Ubah JC +15 more
europepmc +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Structural modelling of student volleyball athletes' intimacy, social adjustment, perceived stress, and learning-related anxiety: mediating role of psychological safety. [PDF]
Li Y.
europepmc +1 more source
Cognitive predictors of social adjustment in pediatric brain tumor survivors treated with photon versus proton radiation therapy. [PDF]
Warren EAH +13 more
europepmc +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Social functioning and support of addicts on methadone
Dragic Natasa +3 more
doaj +1 more source
Correction: The effect of solution-focused approach on social adjustment and solution-focused thinking skills in nursing students who experienced violence in childhood: a single group pre-test-post test study. [PDF]
Tok HH, Akbaş E, Sabancıoğulları S.
europepmc +1 more source
The Effects of Leisure Activities on Self-Efficacy and Social Adjustment: A Study of Immigrants in South Korea. [PDF]
Bum CH, Lee JH, Choi C.
europepmc +1 more source

