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Revisiting Mediation in the Social and Behavioral Sciences
Journal of Methods and Measurement in the Social Sciences, 2013 The process of mediation is of critical importance to the social and behavioral sciences and to evolutionary social psychology in particular. As with the concept of evolutionary adaptation, however, one can argue that causal mediation is in need of ...
Aurelio José Figueredo +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
National Institute of Mental Health Roundtable Discussion: Promissory Notes and Prevailing Norms in Social and Behavioral Sciences Research [PDF]
, 1997 Most workshops convened by the National Institute's of Health are devoted to the puzzle-solving activities of normal science, where the puzzles themselves and the strategies available for solving them are determined largely in advance by the shared ...
Richters, John E.
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Combining the contributions of behavioral economics and other social sciences in understanding taxation and tax reform [PDF]
, 2015 publication-status: Publishedtypes: ArticleThis version uploaded to Munich Personal RePEc ArchivePaper presented at the Conference of the Society for the Advancement of Behavioral Economics, San Diego State University, August 2-5, 2010This paper extends ...
James, Simon
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Consumer Perceptions of Starting Regional Pilot Pay Given Additional Qualifications
International Journal of Aviation, Aeronautics, and Aerospace, 2014 Public Law 111-216, passed in 2010, has drastically increased the required number of flight hours necessary to become a commercial airline pilot from 250 hours to 1,500 hours in the United States.
Scott R. Winter +4 more
doaj +1 more source
BMC Psychiatry, 2022 Background: Internalized stigma can have numerous negative effects on the well-being and employment of people with mental illness. Brief, valid, and reliable measures are needed to get a better understanding of self-stigmatization.
I. E. van Beukering +6 more
doaj +1 more source