Results 91 to 100 of about 3,121,490 (346)

Cultural persistence and change in university students' social networking motives and problematic use

Heliyon
This cross-cultural study assessed the problematic use and motivations of social networking sites (SNS) among university students in China, Malawi, and the UK.
Yamikani Ndasauka, Fiskani Ndasauka
doaj   +1 more source

URBANISASI, MODERNISASI DAN PERUBAHAN SOSIAL PADA KOMUNITAS LOKAL PERKOTAAN: KASUS KOTA BARU METRO TANJUNG BUNGA, MAKASSAR

Tataloka, 2016
This study aims to analyze the spatial physical changes in working as a determinant of social formation changes, processes of social interaction and social adaptation between migrants and local communities in new social formations and consequences of ...
Batara Surya
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Approaching a Viable Comprehension of the Knowledge Society

Teorie vědy, 2010
With different cultures and changing times, a meaning of the same phenomena may vary. This applies also to knowledge in knowledge society: a plurality of bodies of knowledge will be preserved depending on social context, cultural significance, values and
Josef Hochgerner
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

El cambio social

Económica, 1958
The concept of social change refers to alterations and modifications in the social behavior and the cultural values of determinated social systems and structures.
Rex D. Hooper
doaj  

INSTITUTIONAL Change as Cultural Change. An Illustration by Chinese Postsocialist Transformation [PDF]

Culture of a society reflects its social values. So, through Chinese experience, we want to show that institutional change is not only an economic or a political process but fundamentally a cultural one.
EL KAROUNI, Ilyess
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organisational culture and information systems implementation: a critical perspective [PDF]

, 2003
This research explores how information systems (IS) implementation is accomplished when cultural change of an organisation is attempted and what this accomplishment means for those touched by it.
McGrath, Kathy
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source