Results 121 to 130 of about 520,796 (299)
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Virtual Social Networks II, November - December 2011
, 2022 The purpose of the study: to analyse Lithuanian residents attitude towards virtual social networks, behaviour and intensity of involvement in networks. Major investigated questions: respondents were asked if they use internet frequently.
Krupavičius, Algis +6 more
core +1 more source
The Spreading of Information in Online Social Networks through Cellular Automata
Complexity, 2018 Epidemic dynamics in complex networks have been extensively studied. Due to the similarity between information and disease spreading, most studies on information dynamics use epidemic models and merely consider the characteristics of online social ...
Yuda Wang, Gang Li
doaj +1 more source
Information Flow Structure in Large-Scale Product Development Organizational Networks [PDF]
In recent years, understanding the structure and function of complex networks has become the foundation for explaining many different real- world complex social, information, biological and technological phenomena.
Yaneer Bar-Yam, Dan Braha
core
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Digested Information as an Information Theoretic Motivation for Social Interaction [PDF]
Within a universal agent-world interaction framework, based on Information Theory and Causal Bayesian Networks, we demonstrate how every agent that needs to acquire relevant information in regard to its strategy selection will automatically inject part ...
Christoph Salge, Daniel Polani
core
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source