Results 141 to 150 of about 1,161,238 (398)
A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria+5 more
wiley +1 more source
This review brings together recent research from molecular, neural circuit, animal model, and human studies to help understand the neurodevelopmental mechanisms underlying social anxiety disorder.
A. Fox, N. Kalin
semanticscholar +1 more source
Attentional bias and physiological stress sensitivity in children and adolescents with an anxiety disorder [PDF]
Although periods of heightened anxiety are part of normal psychological development (Gullone et al., 2 001; Stevenson-Hinde, & Shouldice, 1995; Westenberg et al., 2 004), a significant proportion of all children and adolescents report anxiety levels ...
Kallen, V.L. (Victor)
core
Separaxion anxiety in pediatric migraine without aura: A pilot study [PDF]
Background: Separation anxiety (SA) can be defined as the fear reaction and protest manifested by children when the main caregivers move away from him/her or in front of unfamiliar person. SA near eight months may be considered as an important and normal
Di Filippo T.+6 more
core +1 more source
Neuroendocrine models of social anxiety disorder
Social anxiety disorder (SAD) is a highly prevalent and disabling disorder with key behavioral traits of social fearfulness, social avoidance, and submissiveness. Here we argue that hormonal systems play a key role in mediating social anxiety, and so may be important in SAD.
van Honk, Jack+4 more
openaire +6 more sources
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song+15 more
wiley +1 more source
Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen+13 more
wiley +1 more source
Antiepileptic Drugs in the Treatment of Anxiety Disorders [PDF]
In addition to epilepsy, antiepileptic drugs are used in neurologic conditions such as chronic pain and in the treatment of bipolar disorder in psychiatry. There are studies reporting its use in the treatment of anxiety disorders.
Levent Mete+2 more
doaj
Taijin kyofusho: a form of social anxiety disorder that responds to serotonin reuptake inhibitors? [PDF]
Hisato Matsunaga+4 more
openalex +1 more source
Irritable Bowel Syndrome patients exhibit depressive and anxiety scores in the subsyndromal range [PDF]
Irritable bowel syndrome (IBS) patients frequently experience affective disorders and psychiatric outpatients frequently meet criteria for IBS. The exact nature of this co-morbidity is not clear. 34 patients with Rome-II diagnosed IBS were recruited from
Hendry, Julie+6 more
core +2 more sources