Results 81 to 90 of about 12,604,585 (206)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Municipal activation policy: A case study of the practical work with unemployed social assistance recipients [PDF]

open access: yes
In the 1990s, many municipalities developed local activation programs for social assistance recipients as a response to increasing social assistance expenditures.
Hjertner Thorén, Katarina
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Minimum Income Protection and Low-Income Standards: Is Social Assistance Enough for Poverty Alleviation? [PDF]

open access: yes
Minimum income protection and social assistance is the last-resort safety net of the welfare state, targeted to the most vulnerable groups in society. Poverty alleviation is thus one chief objective of such benefits.
Nelson, Kenneth
core  

Agrarian change and social assistance outcomes

open access: yes, 2023
This chapter draws together our findings on poverty dynamics and social assistance. First, we consider the predominant patterns of rural change: what is the character of poverty and nutritional security in contemporary Indonesia?
Kutanegara, Pande M.   +8 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Efficiency and equity effects of social grants in South Africa [PDF]

open access: yes
This paper discusses the nature and effects of social grants programmes in South Africa against the backdrop of international trends in the reform of social assistance systems. It shows that South Africa has a well-developed social assistance system that
Bongisa Lekezwa   +2 more
core  

Social Policy Trends: Social Assistance and Inflation

open access: yesThe School of Public Policy Publications
Gaps in the social safety net can widen during periods of inflation. In most circumstances, it is policy choice whether to allow this to occur.
Ronald Kneebone, Margarita Wilkins
doaj   +1 more source

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