Results 121 to 130 of about 2,584,706 (304)

Caught in the Trap? The Disincentive Effect of Social Assistance [PDF]

open access: yes
While financial incentives usually have a significant effect on the labor supply of married women and single mothers, the evidence about the participation elasticity of childless singles, and single males especially, is more scant.
Karina Doorley, Olivier Bargain
core   +6 more sources

Social assistance programme impacts on women's and children's diets and nutritional status. [PDF]

open access: yesMatern Child Nutr, 2022
Olney DK   +5 more
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Welfare and Well-Being; the Treatment of Social Relationships in the Administration of Income Assistance in Ontario

open access: yesCritical Social Work, 2018
Classical economic theory treats the provisioning provided via social relationships as a hindrance to the efficient functioning of market discipline. This view of social relationships has been embodied in recent reforms in the administration of social ...
Stephanie Baker Collins
doaj  

Knowledge and perception of COVID-19 vaccination in two districts of Yaoundé

open access: yesJournal of Public Health in Africa
Background: The coronavirus disease 2019 (COVID-19) pandemic has caused considerable problems throughout the world, with an impact on both public health and economic development.
Michelle S. Djuidje Kamguia   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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