Results 51 to 60 of about 468,155 (259)

Increased kidney disease mortality among people with AIDS versus the general population: a population-based cohort study in Italy, 2006–2018

open access: yesBMJ Open, 2022
Objectives This study aimed to assess whether an excess mortality related to kidney and other urinary tract diseases exists among Italian people with AIDS (PWA), as compared with the general population without AIDS (non-PWA).Design Population-based ...
Diego Serraino   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

BEEING FREE: HABBITS AND DAILY BREAKOUTS IN PRISON ENVIRONMENT [PDF]

open access: yesRevista Română de Sociologie, 2016
Prison is the last possible destination for a humanistic society where the community exert its social, moral and normative borders. A total institution that offers a low mobility and a diminished level of freedom may have contrary effects towards ...
LUCIAN ROTARIU
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

ONLINE PORNOGRAPHY AND SEXUALITY: SOME RESULTS OF EU KIDS ONLINE SURVEY II IN THE ROMANIAN CASE [PDF]

open access: yesRevista Română de Sociologie, 2014
The present article intends to analyze the exposure of Romanian children and teens to sexually explicit message and the so-called „sexting” activities they perform in the online environment. The main research topic to which we try to find some answers is:
VALENTINA MARINESCU
doaj  

Textbooks, Markets, and Meanings: Educational Reform inPostcommunist Romania [PDF]

open access: yesRevista de Știinţe Educaţiei
In 1995, the Romanian government launched the first large-scale education reform since the fall of communism. Largely financed through a World Bank loan, the reform targeted the sector’s core dimensions: mission, content, governance, and subjectivities ...
Dana SOLONEAN
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Social assistance and labour supply [PDF]

open access: yesCanadian Journal of Economics/Revue canadienne d'économique, 1999
The longitudinal, 1988–89 LMAS makes it possible to study the interaction between social assistance and labour supply while allowing for substantial time dependence. Tobit equations for hours worked on and off social assistance, which allow for endogenous selection of social assistance status, are estimated by using FIML.
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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