Results 171 to 180 of about 10,785,096 (340)

Social Support Shopping: Evidence from a Regression Discontinuity in Disability Insurance Reform [PDF]

open access: yes
This paper examines how a change in the generosity of one social assistance program generates spillovers onto other social assistance programs. We exploit an age discontinuity in the stringency of the 1993 Dutch disability reforms to estimate the causal ...
Borghans, Lex   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Social assistance and poverty reduction in Moldova, 2001-2004 an impact evaluation [PDF]

open access: yes
This paper assesses the impact of social assistance benefits on household welfare in Moldova. Ignoring standard issues of impact evaluations such as selection bias, behavioral responses, unobserved heterogeneity and endogeneity, an incidence analysis ...
Verme, Paolo
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Implementation and evaluation of a peer-to-peer support program in oncology: study protocol for the PaRole Onco France model

open access: yesArchives of Public Health
Background Peer support interventions in oncology have shown potential benefits for patients, including reduced psychological distress, improved empowerment, and enhanced care experience.
Yaël Busnel   +13 more
doaj   +1 more source

Sustainability within the Social Assistance System of the Republic of South Africa [PDF]

open access: yes, 2011
The Republic of South Africa is a unique place on the African continent: it was the only place which had a bloodless transition process when the regime changed from a minority government to a democratic one.
Tétényi, András
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Social Jealousy and Stigma: Negative Externalities of Social Assistance Payments in Germany [PDF]

open access: yes
This paper examines the role of social assistance payments (SAP or Sozialhilfe) in determining levels of life satisfaction in Germany using the SOEP 1995–2004. We find strong evidence that individuals in Germany are negatively influenced by increased SAP
John P. Haisken-DeNew   +1 more
core  

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