Results 101 to 110 of about 463,788 (262)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Deaths related to post-COVID in Italy: a national study based on death certificates

open access: yesFrontiers in Medicine
IntroductionSARS-CoV-2 infection has been associated with the onset or persistence of symptoms in the long-term after the acute infection is resolved.
Francesco Grippo   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Social assistance programme impacts on women's and children's diets and nutritional status. [PDF]

open access: yesMatern Child Nutr, 2022
Olney DK   +5 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Welfare and Well-Being; the Treatment of Social Relationships in the Administration of Income Assistance in Ontario

open access: yesCritical Social Work, 2018
Classical economic theory treats the provisioning provided via social relationships as a hindrance to the efficient functioning of market discipline. This view of social relationships has been embodied in recent reforms in the administration of social ...
Stephanie Baker Collins
doaj  

Debt Counseling: The Challenges of Implementation Directive (EU) 2023/2225 within the Romanian Social Services Landscape

open access: yesTransylvanian Review of Administrative Sciences
This article examines the emerging role of debt counseling within Romania’s social services in the context of Directive (EU) 2023/2225. Over-indebt­edness is increasingly recognized across Europe as both an economic and a social risk, with significant ...
Rodica Diana Apan   +1 more
doaj   +1 more source

Home - About - Disclaimer - Privacy