Results 191 to 200 of about 12,750,871 (301)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Social Assistance Monitoring in Social Assistance Policy: Conception and Operation

, 2015
Este texto propõe um debate sobre a Vigilância Socioassistencial, que faz parte dos objetivos da política no Sistema Único de Assistência Social (SUAS). Aborda, especificamente, a base organizacional da gestão no SUAS e o processo da implantação da Vigilância Socioassistencial em Porto Alegre/RS, a partir de 2013.
Martinelli, Tiago, Silva, Marta Borba, dos Santos, Simone Ritta   +2 more
openaire   +1 more source

The constructive power of informality? Relationships, emotion, and empathy in the administration of social assistance for childhood disability in South Africa. [PDF]

Soc Sci Med
Trafford Z.
europepmc   +1 more source

Social Assistance Benefit Rates and the Employment Rate of Lone Mothers [PDF]

The results show that the increase in social assistance benefits has been a major factor behind the decline in employment rates of lone mothers in Ontario.
Kapsalis, Constantine
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Understanding the Reasons Why Patients With Food Insecurity Decline Social Assistance at a Large Academic Medical Center. [PDF]

AJPM Focus
Connelley A, Young A, Lee JT, Miller M, Spring E, Hao W, Wolfson JA, Cohen AJ, Patel MR, Leung CW.   +9 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Persons in helping professions in social assistance facilities and their fears related to COVID-19 using the example of Poland and Spain. [PDF]

Health Psychol Rep
Janus E, Téllez RC, Filar-Mierzwa K, Aleksander-Szymanowicz P, Bac A.   +4 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

How does Internet use impact the mental health of social assistance recipients in China? Examining the chain mediating role of social support and family resilience. [PDF]

Front Psychol
Wu B, Tian B.
europepmc   +1 more source