Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Escaping welfare? Social assistance dynamics in Sweden
The article analyses temporal patterns in social assistance receipt in Sweden in the 2000s by looking at which circumstances facilitate versus reduce the possibilities of a person ceasing to be a recipient of social assistance.
Bergmark, Åke, +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Kansas State Technical Assistance Program.
Includes two Executive Orders and an Executive Appointment by Governor William H.
Kansas. State Technical Assistance Program. Office of the Coordinator.
core
Analysis of Social Assistance and Grant Funds Toward Fisherman Income in Aceh Province [PDF]
From the past until now, the term fishermen or coastal communities has certainly been synonymous with slum environments, poor hygiene and sanitation and high poverty rates.
Chalirafi, Chalirafi, Murtala, Murtala
core
Social Assistance and Successful Advocacy in Georgia: A social protection case study [PDF]
This case study provides information about Oxfam's social protection project that began in Georgia in 2005. Oxfam worked with the Association of Young Economists of Georgia (AYEG) to gather information about household poverty levels, and to ...
Beesley, Jane
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Municipal activation policy: A case study of the practical work with unemployed social assistance recipients [PDF]
In the 1990s, many municipalities developed local activation programs for social assistance recipients as a response to increasing social assistance expenditures.
Hjertner Thorén, Katarina
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

