From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The constructive power of informality? Relationships, emotion, and empathy in the administration of social assistance for childhood disability in South Africa. [PDF]
Trafford Z.
europepmc +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Understanding the Reasons Why Patients With Food Insecurity Decline Social Assistance at a Large Academic Medical Center. [PDF]
Connelley A +9 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Persons in helping professions in social assistance facilities and their fears related to COVID-19 using the example of Poland and Spain. [PDF]
Janus E +4 more
europepmc +1 more source
Social Assistance Monitoring in Social Assistance Policy: Conception and Operation
Este texto propõe um debate sobre a Vigilância Socioassistencial, que faz parte dos objetivos da política no Sistema Único de Assistência Social (SUAS). Aborda, especificamente, a base organizacional da gestão no SUAS e o processo da implantação da Vigilância Socioassistencial em Porto Alegre/RS, a partir de 2013.
Martinelli, Tiago +2 more
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
How does Internet use impact the mental health of social assistance recipients in China? Examining the chain mediating role of social support and family resilience. [PDF]
Wu B, Tian B.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

