SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Machining characteristics and process parameter optimization of Near-dry electrical discharge milling of titanium alloy. [PDF]
Kang S, Zhuo X, Kong L, Li Y, He Y.
europepmc +1 more source
Social Atomism and its Problems – Metaphysical and Political
Social atomism is a view that informs much contemporary social thinking. Drawing on arguments from Marxism and Buddhism, I will argue that it is false, and explore the consequences of this for a number of issues, notably those related to the ideology of capitalism.
openaire +3 more sources
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Guidance framework to apply best practices in ecological data analysis: lessons learned from building Galaxy-Ecology. [PDF]
Royaux C +29 more
europepmc +1 more source
Contests over civil society: introductory perspectives [PDF]
Hall, John A., Trentmann, Frank
core
City of Dreams: Staging an Urban Imaginary [PDF]
Cvetkovich Ann, Derrida Jacques
core +1 more source
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Hybrid XGBoost-RF-MLP model and PSO optimization for performance and emissions of CI engine using waste cooking biodiesel blends. [PDF]
Gad MS, Soliman MS, Helal EB.
europepmc +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source

