Results 91 to 100 of about 5,203,222 (297)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Do you look where I look? Attention shifts and response preparation following dynamic social cues [PDF]

open access: yes, 2012
Studies investigating the effects of observing a gaze shift in another person often apply static images of a person with an averted gaze, while measuring response times to a peripheral target.
Hermens, Frouke, Walker, Robin
core   +3 more sources

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Pupil size and social vigilance in rhesus macaques

open access: yesFrontiers in Neuroscience, 2014
Complex natural environments favor the dynamic alignment of neural processing between goal-relevant stimuli and conflicting but biologically salient stimuli like social competitors or predators.
R Becket Ebitz   +4 more
doaj   +1 more source

Joint attention in the first year: The coordination of gaze and affect between 7 and 10 months of age [PDF]

open access: yes, 2005
We used a multilevel growth model to describe the developmental trajectories of infant’s coordinated attention between people and objects between 7 and 10 months of age.
Stahl, Daniel, Striano, Tricia
core  

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Developmental Changes in Attention to Faces and Bodies in Static and Dynamic Scenes

open access: yesFrontiers in Psychology, 2014
Typically developing individuals show a strong visual preference for faces and face-like stimuli; however, this may come at the expense of attending to bodies or to other aspects of a scene.
Brenda M Stoesz, Lorna S Jakobson
doaj   +1 more source

When to Make the Sensory Social: Registering in Face-to-Face Openings [PDF]

open access: yes, 2020
This article analyzes naturally occurring video-recorded openings during which participants make the sensory social through the action of registering—calling joint attention to a selected, publicly perceiv- able referent so others shift their sensory ...
Pillet-Shore, Danielle M
core   +1 more source

Forecasting environmental equity: Air quality responses to road user charging in Leeds, UK [PDF]

open access: yes, 2005
Sustainable development requires that the goals of economic development, environmental protection and social justice are considered collectively when formulating development strategies. In the context of planning sustainable transport systems, trade-offs
Adebowale   +45 more
core   +1 more source

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