Results 251 to 260 of about 5,140,722 (298)
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
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FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
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FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
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Oxytocin facilitates socially directed attention
Psychophysiology, 2021AbstractSocially directed gaze following is an important component of social interaction and communication, allowing us to attend mutually with others to objects or people so that we can share their experience and also learn from them. This type of joint social attention is impaired in disorders such as autism.
Jiao Le +6 more
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Developmental Psychology, 2004
This study investigated social attention impairments in autism (social orienting, joint attention, and attention to another's distress) and their relations to language ability. Three- to four-year-old children with autism spectrum disorder (ASD; n = 72), 3- to 4-year-old developmentally delayed children (n = 34), and 12- to 46-month-old typically ...
Geraldine Dawson +6 more
openaire +2 more sources
This study investigated social attention impairments in autism (social orienting, joint attention, and attention to another's distress) and their relations to language ability. Three- to four-year-old children with autism spectrum disorder (ASD; n = 72), 3- to 4-year-old developmentally delayed children (n = 34), and 12- to 46-month-old typically ...
Geraldine Dawson +6 more
openaire +2 more sources
Infant social attention predicts preschool social cognition
Developmental Science, 2004AbstractRecent research examining infants’ understanding of intentional action claims to be studying the early origins or precursors of children's later theories of mind. If these infant understandings are continuous with later preschool achievements, there should be empirical connections between the two.
Henry M, Wellman +3 more
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2009
The present chapter suggests that while there is strong evidence that specific brain systems are preferentially biased toward processing gaze information, this specificity is not mirrored by the behavioral data as measured in highly controlled impoverished model tasks.
Birmingham, Elina, Kingstone, Alan
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The present chapter suggests that while there is strong evidence that specific brain systems are preferentially biased toward processing gaze information, this specificity is not mirrored by the behavioral data as measured in highly controlled impoverished model tasks.
Birmingham, Elina, Kingstone, Alan
openaire +3 more sources
How attention gates social interactions
Annals of the New York Academy of Sciences, 2018AbstractSocial interactions are at the core of social life. However, humans selectively choose their exchange partners and do not engage in all available opportunities for social encounters. In this review, we argue that attentional systems play an important role in guiding the selection of social interactions.
Francesca Capozzi, Jelena Ristic
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Neural mechanisms of social attention
Trends in Cognitive Sciences, 2009Social attention is conveyed primarily by gaze, but also by head and body orientation. These cues not only signal a seen agent's direction of attention but are also used to infer their current goals and intentions. Here, we review recent research showing that different gaze, head and body orientations are represented by distinct neural mechanisms, and ...
Lauri, Nummenmaa, Andrew J, Calder
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Zeitschrift für Neuropsychologie, 2003
Abstract: Many TBI patients suffer from cognitive impairments, affecting their abilities to function on a previous level. However, some patients exhibit personality changes, manifesting themselves in inadequate or inappropriate social behavior, which are considered to have even more debilitating consequences on successful social and vocational ...
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Abstract: Many TBI patients suffer from cognitive impairments, affecting their abilities to function on a previous level. However, some patients exhibit personality changes, manifesting themselves in inadequate or inappropriate social behavior, which are considered to have even more debilitating consequences on successful social and vocational ...
openaire +1 more source