Results 251 to 260 of about 4,628,488 (329)

Auditory pallial regulation of the social behavior network. [PDF]

Commun Biol
Spool JA, Lally AP, Remage-Healey L.
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Exploring the effects of dietary lysine and tryptophan on the social behavior of pigs. [PDF]

J Anim Sci
Hewett E, Zaragoza L, Lewis C, Houdijk J, Wilson A, Turner S.   +5 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Three-dimensional markerless motion capture of multiple freely behaving monkeys toward automated characterization of social behavior. [PDF]

Sci Adv
Matsumoto J, Kaneko T, Kimura K, Blanco Negrete S, Guo J, Suda-Hashimoto N, Kaneko A, Morimoto M, Nishimaru H, Setogawa T, Go Y, Shibata T, Nishijo H, Takada M, Inoue KI.   +14 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Anti-social behavior and soccer identities: different continents, same mindset? [PDF]

Self Identity
Newson M, Peitz L, Wibisono S, Knijnik J, White F, Whitehouse H.   +5 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Recovery of centralities in medial prefrontal and sensory-related cortices associated with social behavior improvements in an autism mouse model. [PDF]

Sci Rep
Ueno H, Iyanaga Y, Kunida K, Hara Y, Miura H, Nakai Y, Tanuma M, Hayashida M, Yokoyama R, Ohkubo J, Seiriki K, Hayata-Takano A, Ao T, Yamaguchi S, Kitaoka S, Furuyashiki T, Ago Y, Nakazawa T, Takuma K, Yoshimoto J, Hashimoto H, Kasai A.   +21 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source