Results 261 to 270 of about 16,039,173 (329)
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu+12 more
wiley +1 more source
Effects of 3,4-methylenedioxymethamphetamine on neural activity in the nucleus accumbens of male mice engaged in social behavior. [PDF]
Nishitani N, Sasaki Y, Kaneda K.
europepmc +1 more source
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li+5 more
wiley +1 more source
Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner. [PDF]
Zhao X+7 more
europepmc +1 more source
Social Behavior: A Neural Circuit for Social Behavior in Zebrafish
G. D. Polavieja, M. Orger
semanticscholar +1 more source
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson+5 more
wiley +1 more source
Development of precision medicine approaches to advance clinical trials for autism and social behavior: A research imperative. [PDF]
Boulton KA, Guastella AJ.
europepmc +1 more source
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli+4 more
wiley +1 more source