Results 281 to 290 of about 13,091,254 (361)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Neural cell-types and circuits linking thermoregulation and social behavior. [PDF]

Neurosci Biobehav Rev
Rogers JF, Vandendoren M, Prather JF, Landen JG, Bedford NL, Nelson AC.   +5 more
europepmc   +1 more source

Exam‐level analysis of lecture capture viewing and student exam performance

FEBS Open Bio, EarlyView.
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley   +1 more source

Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior. [PDF]

Science
Barron JJ, Mroz NM, Taloma SE, Dahlgren MW, Ortiz-Carpena JF, Keefe MG, Escoubas CC, Dorman LC, Vainchtein ID, Chiaranunt P, Kotas ME, Nowakowski TJ, Bender KJ, Molofsky AB, Molofsky AV.   +14 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The relationship between subjective social class and pro-social behavior: the mediating role of self-control and the dual-edged sword effect of shame. [PDF]

Front Psychol
Zheng J, Liu H, He Z.
europepmc   +1 more source

Card games are effective tools to enhance foundation year health and safety inductions

FEBS Open Bio, EarlyView.
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq, Holly Matthews, Daniya Abedalreza, Faten Yahya, Matthew Allan Jones   +4 more
wiley   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Laparotomy and burst suppression-inducing sevoflurane induce subtle long-term changes in anxiety and social behavior in late postnatal mice. [PDF]

Korean J Anesthesiol
Zhang T, Lee Y, Ju X, Park J, Hong B, Cui J, Kim Y, Kim S, Choi CH, Heo JY, Chung W.   +10 more
europepmc   +1 more source

Social and Behavioral Science Editorial

Gerontology and Geriatric Medicine, 2015
openaire   +4 more sources