Results 61 to 70 of about 11,994,405 (315)

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures

open access: yesBMC Biology
Background Social behavior and social organization have major influences on individual health and fitness. Yet, biomedical research focuses on studying a few genotypes under impoverished social conditions.
Caleb C. Vogt   +10 more
doaj   +1 more source

Personalized recommendation system based on social relationships and historical behaviors [PDF]

open access: yesarXiv, 2022
Previous studies show that recommendation algorithms based on historical behaviors of users can provide satisfactory recommendation performance. Many of these algorithms pay attention to the interest of users, while ignore the influence of social relationships on user behaviors.
arxiv  

Reciprocal Interactions Between Gut Microbiota and Host Social Behavior

open access: yesFrontiers in Integrative Neuroscience, 2018
Animals harbor an extensive, dynamic microbial ecosystem in their gut. Gut microbiota (GM) supposedly modulate various host functions including fecundity, metabolism, immunity, cognition and behavior. Starting by analyzing the concept of the holobiont as
E. Münger   +3 more
semanticscholar   +1 more source

The role of the striatum in social behavior [PDF]

open access: yesFrontiers in Neuroscience, 2013
Where and how does the brain code reward during social behavior? Almost all elements of the brain's reward circuit are modulated during social behavior. The striatum in particular is activated by rewards in social situations. However, its role in social behavior is still poorly understood.
Raymundo Býez-Mendoza, Wolfram Schultz
openaire   +4 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Why People with More Emotion Regulation Difficulties Made a More Deontological Judgment: The Role of Deontological Inclinations

open access: yesFrontiers in Psychology, 2017
Previous studies have demonstrated the key role of emotion in moral judgment, and explored the relationship between emotion regulation and moral judgment.
Lisong Zhang   +4 more
doaj   +1 more source

The efficient measurement of individual differences in meaning motivation: The need for sense-making short form

open access: yesFrontiers in Psychology, 2022
People differ in the extent to which they express a need for sense-making (NSM), and these individual differences are important to understand in light of meaning-making processes.
Katarzyna Cantarero   +3 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Opinion of Ecuadorians on Migration in the Target Country: Benefits and Challenges

open access: yesSocial Sciences
Migration plays a crucial role in shaping destination countries’ social and economic landscapes, including in Ecuador. This study aims to explore the benefits and challenges of migration by analyzing the perceptions of Ecuadorians who have directly or ...
Angel Torres-Toukoumidis   +2 more
doaj   +1 more source

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