Results 41 to 50 of about 1,457,327 (328)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

General considerations on the enforcement (application) of law

open access: yesJournal of Legal Studies, 2016
Law is a system of norms developed and/or recognized by the state as norms guiding human behaviour according to the values of that particular society, establishing rights and obligations, principles and definitions, structures and relationships of social
Berlingher Remus Daniel   +1 more
doaj   +1 more source

Random model for RNA interference yields scale free network

open access: yes, 2003
We introduce a random bit-string model of post-transcriptional genetic regulation based on sequence matching. The model spontaneously yields a scale free network with power law scaling with $ \gamma=-1$ and also exhibits log-periodic behaviour.
Balcan, Duygu, Erzan, Ayse
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Factors of the deviant behaviour in a legal conscious society

open access: yesLaw and Safety
The article examines the ontology of factors that determine the emergence and development of deviant behaviour. Given the diversity of the concept of deviance, this social phenomenon is comprehensively studied.
S. G. Pevko
doaj   +1 more source

La legitimación de Don Quijote

open access: yesCriticón, 2015
The opposition between natural and positive law leads Don Quixote on a continual search for the legitimization of his actions. Such legitimization of a behaviour that infringes the law draws on the knightly duties described in chivalric treatises and ...
Christoph Strosetzki
doaj   +1 more source

The entropic basis of collective behaviour [PDF]

open access: yes, 2014
We identify a unique viewpoint on the collective behaviour of intelligent agents. We first develop a highly general abstract model for the possible future lives these agents may encounter as a result of their decisions.
Helbing D   +6 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Early modern conceptions of "natural law"

open access: yesActa Academica, 2001
This article traces the shifts in meaning of the metaphor of “natural law” in modern thought from its pre-modern meaning as a divine standard for human behaviour accessible to reason.
Ponti Venter
doaj   +3 more sources

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