Results 161 to 170 of about 12,178,216 (394)

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

open access: yesAdvanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen   +14 more
wiley   +1 more source

Glocal Social Capital

open access: yesGlocalism: Journal of Culture, Politics and Innovation, 2015
Glocalism
doaj   +1 more source

SOCIAL CAPITAL: SYMPATHY, SOCIO-EMOTIONAL GOODS, AND INSTITUTIONS [PDF]

open access: yes
This paper summarizes the current state of the social capital paradigm from the viewpoint of the authors. The paper presents and defends a social capital definition based on sympathetic relationships. The paper also summarizes an expanded set of rational
Robison, Lindon J., Siles, Marcelo E.
core   +1 more source

Rapid Arbitrary‐Shape Microscopy of Unsectioned Tissues for Precise Intraoperative Tumor Margin Assessment

open access: yesAdvanced Science, EarlyView.
This study presents a novel microscopic imaging system capable of rapid, section‐free scanning of irregular tissue surfaces, delivering high sensitivity for detecting cancer cell clusters during intraoperative tumor margin assessment. Abstract Rapid and accurate intraoperative examination of tumor margins is crucial for precise surgical treatment, yet ...
Zhicheng Shao   +17 more
wiley   +1 more source

Are Friendly Farmers Environmentally Friendly? Environmental Awareness as a Social Capital Outcome [PDF]

open access: yes
This paper examines the hypothesis that social capital at the individual level affects environmentally friendly practices. Social capital represents the social connectedness of the individual.
Jordan, Jeffrey L., Munasib, Abdul B.A.
core   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

open access: yesAdvanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang   +10 more
wiley   +1 more source

The Impact of Social Capital on Crime: Evidence from the Netherlands [PDF]

open access: yes
This paper investigates the relation between social capital and crime. The analysis contributes to explaining why crime is so heterogeneous across space.
Akçomak, I. Semih, ter Weel, Bas
core  

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

Globalization, social capital, education

open access: yesПроблеми на постмодерността, 2013
The key thesis of the paper is that social capital is important for integration and civil society, because it is based on different contacts and networks, in which people participate.
Valentina Milenkova
doaj  

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