Results 291 to 300 of about 16,927,067 (395)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

An exploration of the costs of family and group conferencing pathways in adult social care and mental health: A scenario-based cost analysis. [PDF]

PLoS One
Liu L, Tew J, Mahesh S, Kinghorn P.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The Implementation of Knowledge Management in Health and Social Care Organisations as Assessed by Managers: A Descriptive Cross-Sectional Study. [PDF]

Scand J Caring Sci
Karsikas E, Meriläinen M, Koivunen K, Tuomikoski AM, Kanste O.   +4 more
europepmc   +1 more source

Improving diabetes care through the use of social media platform

Shovendra Gautam
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Facilitators and barriers to engaging in expressive writing among health and social care professionals. [PDF]

PLoS One
Smith MA, Hoult LM, Rippon D, O'Brien N, Branley-Bell D, Byrne-Davis L, Collins C, Gallagher S, Kinman G, Mark A, O'Connor DB, Vedhara K, Williams GP, Wetherell MA.   +13 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Birmingham’s city-wide telehealthcare service: how the largest service of its kind in the UK is delivering better for less

International Journal of Integrated Care, 2013
Claire Smith, Jon Tomlinson
doaj  

Exploring Saudi Arabia's care economy in health, education, and social care: a textual analysis using the care diamond framework. [PDF]

Front Public Health
AlSaif AK, AlMubarak SH, Albagmi FM.
europepmc   +1 more source