Results 31 to 40 of about 6,972,461 (360)

Demographic Change, Social Security Systems, and Savings [PDF]

, 2006
In theory, improvements in healthy life expectancy should generate increases in the average age of retirement, with little effect on savings rates. In many countries, however, retirement incentives in social security programs prevent retirement ages from
Bloom, David E, Canning, David, Mansfield, Rick, Moore, Michael   +3 more
core   +2 more sources

Short and long-term effects of disruptive animal rights protest

Humanities & Social Sciences Communications
The climate crisis requires transformational changes to our food systems, which contribute around one third of anthropogenic greenhouse gas emissions. Animal rights activists try to draw attention to this issue through direct action campaigns.
Markus Ostarek, Lennart Klein, Cathy Rogers, James Ozden, Laura Thomas-Walters   +4 more
doaj   +1 more source

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt, Antje Walz, Dietrich Knoerzer   +2 more
wiley   +1 more source

Changing social contracts in climate-change adaptation [PDF]

, 2013
Risks from extreme weather events are mediated through state, civil society and individual action 1 , 2 . We propose evolving social contracts as a primary mechanism by which adaptation to climate change proceeds.
A De Sherbinin, A Weale, CL Johnson, CL Johnson, D Coumou, DA Lavers, G Pryce, G Walker, J Harvatt, JM Jeffers, JS Dryzek, K O’Brien, K O’Brien, K O’Brien, L Whitmarsh, M Pelling, M Pelling, R Few, RW Kates, SE Park, SM Tapsell, T Harries, WN Adger   +22 more
core   +1 more source

"I feel Danish but...": a case study on national identity formation and ambivalence [PDF]

Geographica Helvetica, 2013
Non-western minorities in Europe, one can argue, are experiencing particularly vulnerable processes of subjectification and identification. They are often caught between double processes of inclusion/exclusion, integration/segregation or identification ...
L. Koefoed, K. Simonsen
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

LLM-generated messages can persuade humans on policy issues

Nature Communications
The emergence of large language models (LLMs) has made it possible for generative artificial intelligence (AI) to tackle many higher-order cognitive tasks, with critical implications for industry, government, and labor markets.
Hui Bai, Jan G. Voelkel, Shane Muldowney, Johannes C. Eichstaedt, Robb Willer   +4 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

The Plastic Surgery Workforce and Its Role in Low-income Countries

Plastic and Reconstructive Surgery, Global Open, 2021
Background:. Plastic surgery varies in scope, especially in different settings. This study aimed to quantify the plastic surgery workforce in low-income countries (LICs), understand commonly treated conditions by plastic surgeons working in these ...
Paul Truche, MD, MPH, Ellie Moeller, BS, Taylor Wurdeman, MD, MPH, Kathrin Zimmerman, BA, Norma Cruz, MD, Kiran Nakarmi, MS, MCh, Shankar M. Rai, MBBS, MS, Yegeremu Eado, MD, Laura Pompermaier, MD, PhD, John G. Meara, MD, MBA, D. Scott Corlew, MD, MPH   +10 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source