Results 151 to 160 of about 10,529,438 (341)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On Maskin monotonicity of solution based social choice rules [PDF]

open access: yes, 2007
Haake C-J, Trockel W. On Maskin monotonicity of solution based social choice rules. Working Papers. Institute of Mathematical Economics. Vol 393. Bielefeld: Universität Bielefeld; 2007.Howard (1992) argues that the Nash bargaining solution is not Nash ...
Haake, Claus-Jochen   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Social choice and information: a note on the calculus of mappings from utility spaces [PDF]

open access: yes
Social choice is studied in this paper as a mapping from information on utilities over states of the world to an ordering of those states of the world. The idea of using this type of information originates in the work of Sen and Roberts.
Alex Coram
core  

The effects of a shared history of drug exposure on social choice. [PDF]

open access: yesBehav Pharmacol, 2015
Smith MA   +3 more
europepmc   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Social Choice Theory and the Informational Basis Approach [PDF]

open access: yes
For over a quarter of a century, the use of utility information based upon interpersonal comparisons has been seen as an escape route from the Arrow Impossibility Theorem. This paper critically examines this informational basis approach to social choice.
Kevin Roberts
core  

Social Choice for Agents with General Utilities [PDF]

open access: yes, 2017
The existence of truthful social choice mechanisms strongly depends on whether monetary transfers are allowed. Without payments there are no truthful, non-dictatorial mechanisms under mild requirements, whereas the VCG mechanism guarantees truthfulness ...
Ma, Hongyao, Meir, Reshef, Parkes, David
core  

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