Results 111 to 120 of about 2,854,644 (345)

Mapping Social Choice Theory to RLHF [PDF]

arXiv
Recent work on the limitations of using reinforcement learning from human feedback (RLHF) to incorporate human preferences into model behavior often raises social choice theory as a reference point. Social choice theory's analysis of settings such as voting mechanisms provides technical infrastructure that can inform how to aggregate human preferences ...
arxiv  

Social Choice Theory and Deliberative Democracy: A Reconciliation [PDF]

, 2002
John S. Dryzek, Christian List
openalex   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Multi-Profile Intergenerational Social Choice [PDF]

Ferejohn and Page transplanted a stationarity axiom from Koopmans' theory of impatience into Arrow's social choice theory with an infinite horizon and showed that the Arrow axioms and stationarity lead to a dictatorship by the first generation.
Bossert, Walter, Suzumura, Kotaro
core  

Symbolical Modeling of the Social Development - Combination Theory in the Evolutionary Choice

RUDN Journal of Political Science, 2009
This article focuses on the methods for creating symbolic models of the social development on the basis of mathematical combinations theory, evolutionary theory and variants selection.
D A Misyurov
doaj  

Reality-Aware Social Choice [PDF]

Earlier version in the Proceedings of the 17th International Conference on Autonomous Agents and MultiAgent Systems (AAMAS '18). International Foundation for Autonomous Agents and Multiagent Systems, Richland, SC, 1188-1192. 2018, 2017
Social Choice theory generalizes voting on one proposal to ranking multiple proposals. Yet, while a vote on a single proposal has the status quo (Reality) as a default, Reality has been forsaken during this generalization. Here, we propose to restore this default social state and to incorporate Reality explicitly into Social Choice.
arxiv  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Interpersonal Comparability and Social Choice Theory

The Review of Economic Studies, 1980
At a general level, the information that may be required to enable a planner to judge which of two states is socially preferable may be of a diverse character. It is convenient to partition this information into the welfare and non-welfare characteristics of social states. Welfare characteristics consist of the individual welfares achieved in different
openaire   +3 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source